Hypoxemia
Conditions
Brief summary
There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. This study will assess the effect of wearing two different face masks (disposable and cloth) on blood and muscle oxygenation during cycling exercise.
Detailed description
There is concern that wearing a face mask during exercise will reduce oxygen uptake or increase carbon dioxide re-breathing, which can result in low blood oxygen levels, reduced oxygen delivery to muscle and reduced exercise capacity. The purpose of the study is to determine the effect of wearing two different types of commonly-worn face masks (diposable and cloth) during exercise on blood and muscle oxygenation. Twelve participants who are experienced with cycling will take part in this randomized cross-over study that will assess blood oxygenation (i.e. pulse oximetry) and muscle oxygenation (with near infrared spectroscopy) during a progressive step exercise test to exhaustion. The conditions include no mask, a disposable mask, and a cloth mask. Outcome variables include exercise duration, rating of perceived exertion, blood oxygen saturation levels, and oxygenated, deoxygenated, and total hemoglobin at the quadriceps muscle.
Interventions
OTHERProgressive cycling exercise test to exhaustion
Progressive step cycling exercise test to exhaustion
Sponsors
University of Saskatchewan
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
The individual who will statistically analyze the data will be blinded to condition
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Experienced with cycling
Exclusion criteria
* Contra-indications to exercise as identified by a screening questionnaire (the Get Active Questionnaire)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to exhaustion during exercise | Up to 20 minutes | time to exhaustion |
| Change from baseline in peak power output | Up to 20 minutes | Peak power output in Watts, determined on a cycle ergometer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in blood oxygen saturation | Up to 20 minutes | Blood oxygen saturation as determined by pulse oximetry |
| Change from baseline in quadriceps tissue oxygenation index | Up to 20 minutes | Tissue oxygenation index (oxygenated hemoglobin/total hemoglobin) as measured by near infra-red spectroscopy |
| Change from baseline in rating of perceived exertion | Up to 20 minutes | Rating of perceived exertion on a scale of 1-10 (Modified Borg Scale), a higher score indicates a greater perceived exertion |
| Change from baseline in heart rate | Up to 20 minutes | Heart rate (beats per minute) |
Countries
Canada
Outcome results
None listed