Injection Site Irritation, Pain Syndrome, Propofol Infusion Syndrome
Conditions
Keywords
propofol,injection,pain
Brief summary
Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection. Using an air warmer to warm the arm can also reduce the pain caused by propofol injection. Investors suspect that treatment with a warming patch (covering the injection site) can also reduce the pain caused by propofol injection.
Detailed description
This is a single-center randomized controlled clinical study. Purpose of this study is to explore whether the coverage of the warming patch (for 5min before injection) can reduce the pain induced by propofol injection. The patients included in the study were randomly divided into two groups. The group W used a warming patch to cover the injection site, and the group C used a cotton pad to cover the injection site. After 5 minutes of coverage, the propofol injection was induced, and the patient's complaint of pain (calling or arm withdrawal) during propofol injection was observed, and the patient's recall of the pain score during induction after the patient recovered. After the patients regained consciousness, the data of the two groups were compared to determine whether the use of the warming patch could reduce the pain caused by propofol injection.
Interventions
DEVICEWarming patch
The warming patch can increase the temp of injection site, result in a blood vessels to dilate, which may have some contribute to decreasing injection pain.
DEVICECotton patch
The Cotton patch will cover the injection site as placebo. It dose not have the function of heating comparing to Warming patch.
Sponsors
First People's Hospital of Chenzhou
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
The assessor did not know the grouping of the pain scores in memory, nor did he know the purpose of the warming patch.
Intervention model description
Group W : the injection site was covered with warm patch. Group C: the injection site was covered with Cotton patch.
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* No peripheral phlebitis * No history of Raynaud's syndrome * No history of smoking or alcoholism * Body mass index BMI\<28 kg/cm2
Exclusion criteria
* Refusal of anesthesia * Previous injection pain caused by propofol * Difficulty in exposing the veins on the back of the hand or difficulty in venipuncture * Complained of pain after normal saline infusion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Arm withdrawn | 5min | When propofol was injected, the arm was withdrawn due to injection pain. |
| Complaints of pain | 5min | The patient complained about the pain of the propofol injection |
| Pain score after awakening from propofol | 10min | Let the patients give a score when they recoved from propofol induced anesthesia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory depression | 5min | those ases when pulse oxygen saturation is less than 90% |
| Temperature of injection site after injecting of propofol. | 10min | Get the temperature of the back of the hand with an infrared thermometer |
Countries
China
Outcome results
None listed