Total Hip Arthroplasty
Conditions
Brief summary
Total hip arthroplasty (THA) is one of the main elective orthopedic surgery. Recent studies have proven that patients undergoing an elective THA who are part of a fast track surgery program including an opioid free anesthesia (OFA) presented a decrease of mortality and a reduced in-hospital length of stay. Based on the anatomical knowledges, the Quadratus Lumborum Block seems to be an interesting locoregional technique for patients undergoing THA. So far, there is no recommanded locoregional aesthesia in this indication. The investigators hypothezised that QLB would give an efficient analgesia in the 24h following a THA. Therefor, the study performed a prospective, randomized, double blind trial in the Nice Universitary hospital of Pasteur 2 and in Arnault Tzanck Institute among all patients who underwent THA, comparing a QLB using ropivacaïne 2mg/ml 20ml vs isotonic saline solution 20 ml.The main end-point is the decrease opiod consumption in the 24h following THA.
Interventions
DRUGRopivacaine injection
Realization of the quadratum lumborum block type 3, ultrasounds' guided by the injection of 20 ml of ropivacaïne 2 mg/ml
OTHERNACL
Realization of the quadratum lumborum block type 3, ultrasounds' guided by the injection of 20 ml of NACL
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• All adult patients with unilateral programmed total hip prosthesis surgery are included in the absence of inclusion criteria. * Obligation for all patients to be affiliated with social security * Patient Informed Consent Signature
Exclusion criteria
* chronic opiod consumption * pregnancy * mental disorder that prevents the usage of the numeric analog scale * Contra indications of the realization of QLB * Local infection * Allergic to the local anesthesia * Hemostasis disorder * Incapacity of giving the consent : individuals under guardianship by court order, or under judicial protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Opoïd consumption | At 24 Hours | The main end point of this study is the decrease of opiod consumption in the 24h following THA. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| morphine equivalent dose | At 48 Hours | following surgery at rest and in motion |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORRozier Romain
Anesthésie Réanimation - CHU de Nice
Outcome results
None listed