Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04555018

Enrollment

Registered

2020-09-18

Start date

2017-06-01

Completion date

2017-10-01

Last updated

2020-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris, Female

Keywords

Acne vulgaris, Sebum level, Dehydroepiandrosterone Sulfate

Brief summary

The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. A cross sectional study was conducted with 50 samples, in June to October 2017.

Detailed description

Epidemiological studies have shown that number of adult female acne vulgaris (AV) increases. Hormone, sebum production, Propionibacterium acne and inflammatory process are factors involved in AV development. The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. This research used cross sectional study with 50 samples, aged 25-49 years by consecutive sampling. The degree of acne vulgaris was evaluated using Lehman criteria , and then the sebum level and DHEAS were measured objectively using sebumeter and serum, respectively.

Interventions

None listed

Study design

Observational model

CASE_CROSSOVER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 49 Years

Inclusion criteria

* Female, age 25-29 years * Diagnosed with mild to severe acne vulgaris * Agree to participate

Exclusion criteria

* History of taking antiandrogen drugs * History of taking oral and topical antibiotics, using topical retinoid and BPO in the last 4 weeks * History of taking oral isotretinoin in the last 6 months * Pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame	Description
Sebum level	One day	Using sebumeter to evaluate the sebum level objectively
Dehydroepiandrosterone sulfate	One day	Blood serum was used to evaluate Dehydroepiandrosterone sulfate level.

Countries

Indonesia

Outcome results