Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

Evaluation of the Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04551612

Enrollment

Registered

2020-09-16

Start date

2020-10-01

Completion date

2022-10-01

Last updated

2020-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholesteatoma, Middle Ear

Brief summary

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations

Detailed description

Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type

Interventions

RADIATIONMultislice computed tomography temporal bone

Patients with cholesteatoma will undergo multislice computed tomography (MSCT) temporal bone images. Then The Tegmen level will be determined and compared with the other normal ear at the same patient

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All adults above the age of 18 presented to the Assiut university Clinic with cholesteatoma will be included in the study.

Exclusion criteria

1. Patients with previous mastoid surgery 2. Patients with Craniofacial anomalies or cleft lip and palate 3. Pediatric populations ≤ 18 years old 4. Patients with congenital ear anomalies

Design outcomes

Primary

Measure	Time frame	Description
Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.	One year	determination the level of tegmen in patients with attico-antral diseases by MSCT

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026