Recurrence of Overactive Bladder Syndrome
Conditions
Keywords
overactive bladder syndrome, beta-3 agonist, retreatment
Brief summary
Recurrence of female overactive bladder syndrome (OAB) is not uncommon. It is important to decrease the recurrence of female OAB. However, factors predicting recurrence of female OAB, especially for those women who need retreatment is undetermined. Thus, the aim of this study was to elucidate factors predicting retreatment of female OAB.
Detailed description
The medical records, including pad testing, urodynamic studies, lower urinary tract symptoms related questionnaires and bladder diaries of all consecutive women with OAB, who visited urogynecologic clinics in a tertiary referral center, were reviewed. Persistence interval was defined from the date of prescription of mirabegron to the date of discontinuation of mirabegron treatment. Statistical analysis was performed with Kaplan-Meier estimator. Multivariable Cox proportional-hazard model with all variables with p \< 0.25 in the univariate analysis was performed to predict OAB retreatment probability.
Interventions
Mirabegron 25 mg per day
Sponsors
Study design
Eligibility
Inclusion criteria
* Women with overactive bladder syndrome * Women complete urodynamic study and bladder diary
Exclusion criteria
* Pregnant women * Incomplete data * Loss of follow-up * Acute or chronic urinary tract infection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrent OAB | January 2015 to July 2019 | Recurrent OAB with needs to retreatment |
Countries
Taiwan