Rate of Spontaneous Stone Passage as Assessed Using Urinary Ultrasonography and Direct Urinary System Radiography

Evaluation of the Effect of Masturbation on Distal Ureteral Stones: A Prospective Randomized Controlled Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04550559

Enrollment

149

Registered

2020-09-16

Start date

2018-02-01

Completion date

2020-03-31

Last updated

2020-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Masturbation, Ureteral Calculi

Brief summary

To evaluate the effect of masturbation on the spontaneous expulsion of distal ureteral stones 5-10 mm in size.

Detailed description

This prospective randomized controlled study was performed between February 2018 and March 2020 after obtaining ethics committee approval.A total of 128 men with distal ureteral stones were randomly divided into 3 groups. All patients received standard medical therapy. Patients in group 1 (n=43) were instructed to masturbate at least 3-4 times a week, patients in group 2 (n=41) received tamsulosin 0.4 mg/day, and patients in group 3 (controls, n=44) received standard medical therapy alone. Rates of expulsion, need for analgesic, and ureterorenoscopic lithotripsy were compared between the groups.

Interventions

PROCEDUREEndoscopic ureterolitotripsy

Endoscopic ureterolithotripsy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* age ≥18 years * presenting with renal colic and inguinal or lumbar pain * being diagnosed as having distal ureteral stones ≥5 mm and \<10 mm in size

Exclusion criteria

* age \<18 years, * stones \<5 mm or ≥10 mm in size, * intermediate (stones on the ureter-iliac artery cross) * proximal ureteral stones, multiple ureteral stones, * presence of urinary infection, * renal insufficiency, * high creatinine level, * severe hydroureteronephrosis, * history of open or endoscopic ureteral surgery, * vesicoureteral reflux, * neurogenic bladder, * erectile dysfunction, * inability or refusal to masturbate for any reason (such as religious beliefs)

Design outcomes

Primary

Measure	Time frame	Description
The rates of spontaneous distal ureteral stone (5-10 mm size) passage after 4 weeks masturbation	4 weeks	The rates of spontaneous distal ureteral stone (5-10 mm size) passage of patients who were instructed to masturbate at least 3-4 times a week (Group1); received tamsulosin 0.4 mg/day (Group2); received standard medical therapy alone Group3.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026