L1 M1 of LDCT for Low Muscle Mass Measurement

Evaluation of Low Muscle Mass by Muscle Surface Index of First Lumbar Vertebrae Using Low Dose Computed Tomography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04547478

Enrollment

3304

Registered

2020-09-14

Start date

2019-01-21

Completion date

2020-07-10

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Brief summary

The first lumbar spine muscle index (L1 MI) on computed tomography (CT) obtained by measuring muscle surface at the first lumbar vertebrae (L1) level is an indicator of total skeletal mass in specific populations. Nevertheless, the utility of L1 MI derived from low dose chest CT (LDCT) in health assessments and relevant cutoff points are unclear.

Interventions

DIAGNOSTIC_TESTlow dose chest CT(LDCT)

cross sectioned muscle area of the 1st vertebrae level obtained by LDCT

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adults older than 20 years who received LDCT in routine health assessments from January to December 2017 were enrolled at a tertiary care hospital (Far Eastern Memorial Hospital, New Taipei City, Taiwan).

Exclusion criteria

* nil

Design outcomes

Primary

Measure	Time frame	Description
Cross sectional muscle area of the 1st vertebrae level	52 weeks	Cross sectional muscle area of the 1st vertebrae level by LDCT

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026