Study of Retinal Vascular Changes After Ocular Blunt Trauma

Retinal Vascular Features in Ocular Blunt Trauma by Optical Coherence Tomography Angiography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04546997

Enrollment

Registered

2020-09-14

Start date

2019-01-10

Completion date

2019-12-30

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Injury

Brief summary

This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.

Detailed description

To investigate, using optical coherence tomography angiography, early retinal vascular features 48 hours after ocular trauma and to detect their changes during 6 months' follow up. The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed analysis of retinal vascular features.

Interventions

DIAGNOSTIC_TESTOptical Coherence Tomography Angiography

Patients underwent non-invasive, fast, diagnostic imaging technique (optical coherence tomography angiography)

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* age older than 40 years * diagnosis of previous ocular blunt trauma * absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * absence of significant lens opacities, low-quality OCT and OCT-A images.

Exclusion criteria

* age younger than 40 years * absence of previous ocular blunt trauma * presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * presence of significant lens opacities, low-quality OCT and OCT-A images.

Design outcomes

Primary

Measure	Time frame	Description
The measurements of retinal vessel density in patients after ocular blunt trauma during 6 months's follow up	Six months	To evaluate the changes in retinal vessel density in 18 patients, at baseline and 1, 3, 6 months after ocular blunt trauma, using optical coherence tomography angiography. The parameter analyzed by optical coherence tomography angiography was: retinal vessel density

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026