Thromboses, Venous, Varicose Veins of Lower Limb, Venous Insufficiency
Conditions
Brief summary
A prospective study of individuals without varicose veins and who have primary varicose veins to assess the morbidity, risk factors and natural course of chronic lower limb vein disease.
Detailed description
Multicenter prospective cohort observational study based on a termless epidemiological registry. Periodic inspection and collection of data from the subjects is carried out annually, in the last quarter of the current year. Patient data is recorded in a digital database and is constantly updated
Interventions
None listed
Sponsors
Russian Phlebological Association
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
10 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* A family members of the researcher (spouse, childrens, brothers and sisters, parents) or the researcher himself * The possibility of annual clinical and ultrasound assessment of the venous system of the observed individuals
Exclusion criteria
* Any invasive treatment of the chronic venous disorder in anamnesis * Venous thrombosis in the anamnesis or at the time of inclusion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of primary varicose veins | 1 year | Number of Participants with the first identified varicose veins (class C2 according to CEAP classification) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Progression of primary varicose veins | 1 year | The presence of varicose veins in new areas of the lower extremites (each limb is divided into 8 areas: thigh - anterior, posterior, medial, lateral area; lower leg - anterior, posterior, medial, lateral area) |
| Incidence of chronic venous insufficiency | 1 year | Number of participants with the first identified sign of chronic venous insufficiency (venous edema, venous eczema, hyperpigmentation of the skin, lipodermatosclerosis, venous ulcer) |
| Incidence of superficial vein thrombosis | 1 year | Number of participants with first episode of superficial vein thrombosis |
| Incidence of reticular and telangiectatic leg veins | 1 year | Number of Participants with the first identified eticular and telangiectatic leg veins ((class C1 according to CEAP classification) |
| Progression of reticular and telangiectatic leg veins | 1 year | The presence of reticular and telangiectatic leg veins in new areas of the lower extremites (each limb is divided into 8 areas: thigh - anterior, posterior, medial, lateral area; lower leg - anterior, posterior, medial, lateral area) |
Countries
Russia
Outcome results
None listed