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Impact of Labor and Delivery on Ultrasound Measured Cricothyroid Membrane Depth and Height

Impact of Labor and Delivery on Ultrasound Measured Cricothyroid Membrane Depth and Height

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04546087
Enrollment
50
Registered
2020-09-11
Start date
2020-09-01
Completion date
2022-11-02
Last updated
2024-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway Complication of Anesthesia

Keywords

cricothyroid membrane, pregnancy, ultrasound

Brief summary

The cricothyroid membrane acts as a route through which the upper airway can be accessed to provide oxygen and ventilation to patients. Anesthesiologists need to deliver oxygen and ventilation to patients under general anesthesia, where patients may lose the ability to breath for themselves. Access through this membrane to provide oxygen and ventilation is critical in emergency situations where other traditional means to access the airway (e.g. through endotracheal ventilation, supraglottic airway devices or face mask ventilation) have failed. It is known, from previous studies, that due to the physiological changes that occur in labour, the upper airway of the body undergoes changes that can make accessing the airway through traditional means more difficult, specifically during the period of labor, delivery, and just after delivery. Ultrasound is becoming increasingly popular due to its ability both to identify the cricothyroid membrane and to improve success in accessing the airway through the cricothyroid membrane. What is not known, and has not been studied to date, is specifically how the anatomy (i.e. its height and its depth) specifically changes during the period of labour, delivery and just after delivery. The aim of this study would be to scan (using ultrasound) pregnant women's necks once at the very start of their labour, and once within 4 hours of delivery of their baby, to identify how the size and depth of the cricothyroid membrane changes. This information would improve the understanding of how to best approach accessing this membrane in laboring pregnant women. The investigators hypothesize that in labouring third trimester patient, that the depth to the cricothyroid membrane will increase, and there will be no change in the cricothyroid membrane height.

Interventions

DEVICEUltrasound

Ultrasound scan of the cricothyroid membrane

Sponsors

Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Age \>=18 years old * Pregnant patients in third trimester (\>28/40 weeks) * Ability to understand the rationale of the study assessments and to provide signed consent.

Exclusion criteria

* Neck arthritis * Cervical stenosis * Known cervical degenerative disc disease * Rheumatoid Arthritis * Any restriction of neck movement * Upper limb neurology * Patient refusal * Patients not in established labour. * Patients undergoing cesarean section * Known distorted airway anatomy

Design outcomes

Primary

MeasureTime frameDescription
Cricothyroid membrane position change24 hoursDifference between the depth from the skin to the cricothyroid membrane- tracheal interface change ultrasound between the onset of established labor and following delivery of the baby and placenta.

Secondary

MeasureTime frameDescription
Cricothyroid membrane size change24 hoursDifference between the height of the cricothyroid membrane (CTM) at the onset of established labor and the height of CTM following delivery of the baby.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026