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Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04546061
Enrollment
112
Registered
2020-09-11
Start date
2020-09-15
Completion date
2023-01-25
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental Health, Substance Use

Keywords

Sexual and Gender Minorities, Substance Use and Mental Health Treatment, Mental Health, Substance Use, Minority Stress, Young Adults, Intensive Case Management, Peer Support

Brief summary

This study provides substance use and mental health treatment for young sexual and gender minority adults in Durham and Charlotte, NC and seeks to provide intensive wraparound services that address factors that influence substance use and mental health among this population such as minority stressors and lack of social support, housing instability, lack of access to affirmative health care, and limited job opportunities.

Detailed description

Project Uplift provides evidenced-based substance use and mental health treatment, intensive case management, and peer support services for sexual and gender minorities, ages 18-35. The program is based in two metropolitan areas in North Carolina, Durham and Charlotte, and will offer services for approximately 80 sexual and gender minority young adults. Survey data collected from participants at baseline and at the end of the 6-month program will be used to evaluate the effectiveness the comprehensive care program.

Interventions

BEHAVIORALProject Uplift

Substance use and mental health treatment for young sexual and gender minorities in Durham and Charlotte, NC in conjunction with intensive wraparound services that address factors that influence substance use and mental health among this population.

Sponsors

Duke University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

1) age 18-35; 2) substance use in the last 90 days; 3) self-identify as a sexual and/or gender minority; 4) reside in the Durham or Charlotte geographic areas including neighboring counties

Exclusion criteria

1) inability to speak and read English

Design outcomes

Primary

MeasureTime frameDescription
Change in substance use from baseline to 6-month follow-upBaseline and 6-monthsAddiction Severity Index collected via a computer assisted self-interviewing survey
Change in mental health status from baseline to 6-month follow-upBaseline and 6-monthsBrief Symptom Inventory collected via a computer assisted self-interviewing survey

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026