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Earliest Lung Ultrasound Time for Predicting the Need of Surfactant

Earliest Lung Ultrasound Time for Predicting the Need of Surfactant

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04544514
Enrollment
71
Registered
2020-09-10
Start date
2017-01-01
Completion date
2019-12-31
Last updated
2020-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Distress Syndrome

Brief summary

Lung ultrasonography (LUS) is fast and easy technique. it also has high reliability, so it has started to be used more in evaluating respiratory distress in the neonatal period. The most important feature of LUS is being radiation-free. Three LUS findings that show respiratory distress syndrome were described. They were white lung appearance, lack of preserved areas and loss of pleural integrity. The sensitivity of these findings was found to be 98-100% and the specificity 92-100%. A few studies have shown that surfactant need can be determined by LUS. It was observed that lung findings were more severe in LUS performed in the early period because of non-completed fetal lung fluid clearence, but the findings could be improved during follow-up. Therefore, it is not known when the earliest time of LUS shows the actual clinical condition and course of the patient. This study was planned to find the most reliable and earliest US time. Evaluation with LUS was done at 30 minutes and repeated at 1, 2, 4 and 6 hours of life. The LUS findings would be compared with x-ray findings and the correlation of surfactant need with LUS findings would also be investigated.

Interventions

DIAGNOSTIC_TESTlung ultrasound

LUS was performed within first 20 to 30 minutes and repeated at 1, 2, 4 and 6 hours.

Sponsors

Gozdem Kayki
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
30 Minutes to 6 Hours
Healthy volunteers
No

Inclusion criteria

* preterm babies with a gestational age 32 weeks or less * babies treated with CPAP

Exclusion criteria

* If a baby was intubated in delivery room because of the responsiveness to face-mask ventilation, he/she was excluded. * congenital heart diseases * complex congenital malformations * chromosomal abnormalities.

Design outcomes

Primary

MeasureTime frameDescription
lung ultrasound at 30 minutes30 minuteslung ultrasound findings
lung ultrasound at 1 hour1 hourlung ultrasound findings
lung ultrasound at 2 hour2 hourlung ultrasound findings
lung ultrasound at 4 hour4 hourlung ultrasound findings
lung ultrasound at 6 hour6 hourlung ultrasound findings

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026