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COVID-19 in a Single Large UK Rheumatology Centre and Impact on QOL

COVID-19 Prevalence in a Single Large UK Rheumatology Centre and the Impact on Quality of Life From Stringent Social Distancing

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04542031
Acronym
CRISP
Enrollment
1010
Registered
2020-09-09
Start date
2020-12-14
Completion date
2022-02-01
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Rheumatic Diseases

Brief summary

The COVID-19 pandemic represents a threat to rheumatology patients. National advice for patients to 'shield' is based on risk stratification of therapies and other risk factors. While the epidemiology of COVID-19 in the rheumatological population is largely unknown large case registries are beginning to show potential drug treatment interactions. Strict self-isolation (shielding) has been recommended for those deemed 'high risk' although its impact on the likelihood of COVID-19 infection and health related quality of life (HRQoL) is unclear. The study aims to explore how this unprecedented situation has impacted the Trust patients primarily evaluating prevalence of the infection, effect of stringent social distancing (shielding) and Quality of Life (QOL). This will be done via a voluntary questionnaire, sent via text messaging at 6 and 12 months.

Interventions

OTHERQuestionnaire

Questionnaire to be completed at 6 and 12 months

Sponsors

The Royal Wolverhampton Hospitals NHS Trust
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All rheumatology patients under active follow up at the Royal Wolverhampton Trust with a validated mobile telephone number

Exclusion criteria

* Patients without a validated mobile phone number linked to their hospital record

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of COVID 191 yearpercentage of cases
Mortality rates from COVID 191 yearnumber of deaths per 1000 individuals
Health related quality of life - Short Form 121 yearmental and physical component scores through patient reported outcomes. Normative score set at 50 with minimum score being 0 and maximum score being 100. Scores \>50 indicate better mental or physical health than the mean. Scores \<50 indicate worse mental or physical health than the mean

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026