Healthy
Conditions
Keywords
supplementation, ergogenic aid, metabolic rate, energy, substrate utilization
Brief summary
The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise. The effects of these substances on substrate utilization, gas exchange, and psychological factors were also investigated. Twelve males (mean ± SD: age = 22.8 ± 2.4 years) completed three bouts of 60-min of treadmill exercise at 4.8-6.4 km/hr on separate days after consuming a pre-workout supplement, 6 mg/kg of caffeine, or placebo in a randomized fashion. The pre-workout and caffeine supplements resulted in significantly greater energy expenditure (p \< 0.001, p = 0.006, respectively), VO2 (p \< 0.001, p = 0.007, respectively), VCO2 (p = 0.006, p = 0.049, respectively), and VE (p \< 0.001, p = 0.007, respectively), but not rates of fat or carbohydrate oxidation or respiratory exchange ratio compared to placebo (collapsed across condition). In addition, the pre-workout supplement increased feelings of alertness (p = 0.015) and focus (p = 0.005) 30-minutes post-ingestion and decreased feelings of fatigue (p = 0.014) during exercise compared to placebo (collapsed across condition). Thus, the pre-workout supplement increased energy expenditure and measures of gas exchange to the same extent as 6 mg/kg of caffeine with concomitant increased feelings of alertness and focus and decreased feelings of fatigue.
Interventions
DIETARY_SUPPLEMENTENGN Shred
ENGN Shred is a multi-ingredient pre-workout supplement.
DIETARY_SUPPLEMENTNutricost caffeine powder
Caffeine powder.
DIETARY_SUPPLEMENTCrystal Light
Non-caloric Crystal Light matched for the pre-workout in terms of flavor and consistency.
Sponsors
Northern Illinois University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
19 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
* Male
Exclusion criteria
* history of medical or surgical events, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders; * use of any medications * use of nutritional supplements * habitual use of caffeine (≥1 caffeinated beverage per day) * participation in another clinical trial or investigation of another investigational product within 30 days prior to screening/enrollment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Energy expenditure | Measured continuously during 60 minutes of exercise for all three supplement conditions | Measurement of caloric expenditure via gas exchange |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Carbon dioxide production | Measured continuously during 60 minutes of exercise for all three supplement conditions | Measurement of rate of carbon dioxide production using a metabolic cart |
| Minute ventilation | Measured continuously during 60 minutes of exercise for all three supplement conditions | Measurement of ventilation rate using a metabolic cart |
| Feelings of fatigue | Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions | Subjects were asked to rate their feelings of fatigue using a 5-point Likert scale |
| Feelings of energy | Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions | Subjects were asked to rate their feelings of energy using a 5-point Likert scale |
| Oxygen consumption | Measured continuously during 60 minutes of exercise for all three supplement conditions | Measurement of rate of oxygen consumption using a metabolic cart |
| Feelings of alertness | Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions | Subjects were asked to rate their feelings of focus using a 5-point Likert scale |
| Rate of fat oxidation | Measured continuously during 60 minutes of exercise for all three supplement conditions | Fat oxidation was estimated thru measurements of gas exchange |
| Rate of carbohydrate oxidation | Measured continuously during 60 minutes of exercise for all three supplement conditions | Carbohydrate oxidation was estimated thru measurements of gas exchange |
| Feelings of focus | Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions | Subjects were asked to rate their feelings of focus using a 5-point Likert scale |
Countries
United States
Outcome results
None listed