Mortality Score in Elderly Patients With Colon Cancer

Score for the Prediction of Mortality Risk After Surgery for Colon Cancer in a Case Series of Elderly Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04538404

Acronym

MECC

Enrollment

385

Registered

2020-09-04

Start date

2011-01-01

Completion date

2019-01-31

Last updated

2020-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Mortality, Surgery

Keywords

colon cancer, surgery, mortality, elderly, scoring system

Brief summary

CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a purely preoperative risk assessment. The primary aim of the study is to develop a new surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population. The secondary objective is to analyze its efficacy compared to CR-POSSUM.

Detailed description

Patients aged 80 and older undergoing surgery for colon cancer from 2011 to 2017 in an Italian hospital were retrospectively selected. MECC score \[Mortality in Elderly patients with Colon Cancer\] was calculated summing up the scores relating to: arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine. Once CR-POSSUM was calculated, the two scores were compared.

Interventions

PROCEDUREColon Surgery

Right, left colon surgery, transverse colon surgery, multiple colon surgery in open and minimally invasive surgert

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

80 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 80 and above having elective and emergency colonic resection for colon cancer via open, laparoscopic and converted approaches

Exclusion criteria

* Surgical resections for rectal cancer and surgical procedures for non-neoplastic colon pathologies

Design outcomes

Primary

Measure	Time frame	Description
New surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population	Up to 30 days after surgery	MEC Score (arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine) for the evaluation of the risk of in-hospital mortality occurred during hospitalization up to 30 days

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026