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Clinical Significance of Whitnall Ligament Structure

Clinical Significance of Whitnall Ligament Structure in Patients With Congenital Ptosis

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04537169
Enrollment
45
Registered
2020-09-03
Start date
2020-08-20
Completion date
2021-09-30
Last updated
2020-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Ptosis

Keywords

Whitnall ligament, congenital ptosis, levator resection

Brief summary

Prospective clincal study to relate the structure of Whitnall ligament in cases of congenital ptosis to the severety of ptosis and the postoperative results.

Detailed description

The study will be a prospective obsevational study. It will include patients (2-16 years old) who will undergo levator resection for simple congenital ptosis correction in Ophthalmology Department of Menoufia University Hospital. Patients will be divided into 3 groups, 15 patients in each. Group I for mild ptosis, Group II for moderate ptosis Group 3 for severe ptosis. Exclusion criteria included any patients with previous ptosis or any eyelid surgery and patients with a non congenital ptosis. Patients included in the study well be informed about the research and the surgical maneuver which will be used with full discussion of all details regarding the postoperative follow up and the potential complications. A written consent in Arabic will then be taken from the parents of the patients Preoperative assessment will include Complete ophthalmological examination including; Margin to Reflex Distance 1 (MRD1), Vertical Fissure Height (VFH), Levator function (LF), and eyelid crease shape and position. Intraoperative assessment will include Whitnall ligament structure assessment including: * The level (the length from the insertion of the levator aponeurosis to Whitnall's ligament) * Shape (definite band-like, weak string, undifferentiated) * Tightness. Postoperative assessment will be on scheduled visits at first week, one month, 3 months and 6 months postoperatively and will include MRD1, VFH, LF, and lagophthalmos measurements Results will be documented and tabulated and statistically managed.

Interventions

Eyelid crease incision Dissection of the levator aponeurosis to the level of Whitnall ligament. Assessment of the structure of Whitnal ligament. Resection of a calculated part of the aponsurosis. re-attachment of the aponeurosis to the tarsus Incision closure with crease formation

Sponsors

Menoufia University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
2 Years to 16 Years
Healthy volunteers
No

Inclusion criteria

* Congenital ptosis

Exclusion criteria

* Previous ptosis surgery * Non congenital ptosis

Design outcomes

Primary

MeasureTime frameDescription
Success of levator resection in relation to structure of Whitnall ligamentAn average of 1 yearRelating the structure of the ligament with the degree of severity of ptosis by studying its position, shape and tightness in all cases during surgery

Countries

Egypt

Contacts

Primary ContactSameh S Mandour, M.D.
dr_ssmandour@hotmail.com01113139138
Backup ContactMostafa M Diab, M.D.
mmd11@fayoum.edu.eg01016737314

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026