17β-Estradiol, Burning Mouth Syndrome, Dehydroepiandrosterone, Hormone Disturbance, Progesterone, Quality of Life
Conditions
Keywords
burning mouth syndrome, hormonal status, quality of life
Brief summary
The aim of this study was to determine the level of salivary estradiol, progesterone and dehydroepiandrosterone in female postmenopausal women with and without burning mouth syndrome. In all participants the quantity of unstimulated and stimulated saliva would be determined and they would fulfill self-perceived quality of life questionnaire Oral Health Impact Profile-14 (OHIP-14). Intensity of burning symptoms would be determined on visual-analogue scale grading 0-10. All data would be compared between study and control group.
Interventions
DIAGNOSTIC_TESTunstimulated saliva sample for hormone analysis
hormone levels will be determined in frozen samples of unstimulated saliva
OTHERquality of life questionnaire
all participants will fill out self-perceived quality of life questionnaire
Sponsors
University of Zagreb
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
51 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* postmenopausal women with burning mouth syndrome
Exclusion criteria
* women with burning mouth syndrome who are not in menopause
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| to evaluate the levels of salivary hormone | November 2019-June 2020 | levels of salivary 17β-Estradiol, progesterone and DHEA were determined in study and control group |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| to evaluate quality of life and correlate it with levels of salivary hormones and intensity of symptoms | November 2019-June 2020 | quality of life was evaluated with self-perceived questionnaire OHIP-14 |
Countries
Croatia
Outcome results
None listed