Aging, Cognitive Decline
Conditions
Keywords
exercise, resistance training, kinesiology, cognition, ERP, neuroimage
Brief summary
This study investigated the effect of acute multiple joint, structural barbell resistance exercise on information processing speed and conflict-related neural activity in older adults via a crossover, sham control, randomized control trial.
Interventions
BEHAVIORALResistance exercise
Barbell back squat, press, and deadlift for three sets of five repetitions with the weight closest to 75% of their estimated 1 repetition max. The participants were instructed to execute the movement with moderate speed (2s eccentric, 2s concentric, no pause in between). The rest period between sets and exercise movements was two to three minutes.
BEHAVIORALStretching exercise (sham exercise)
Participants completed a passive stretching exercise session for a similar duration of time as the resistance exercise (≈ 30 min) as sham intervention, which included 15-20 stretching movements twice, holding each for 30 seconds as recommended by ACSM.
Sponsors
National Taiwan Normal University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
50 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. male adults aged 50-65 years old 2. exercise ≥ 150 minutes/week 3. normal or corrected-to-normal vision 4. right-handed
Exclusion criteria
1. dementia (MMSE ≥ 24) 2. any medical condition listed on PARQ 3. depression (BDI-II score ≤ 13) 4. any diagnostic cardiovascular, neurological and other chronic diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of Information processing speed between resistance and stretching exercises | 5-30 minutes before and 10-35 minutes after each intervention. | Choice reaction time of the Stroop test congruent condition. Unit: millisecond. Shorter reaction time means a better outcome. |
| Change of Inhibitory control between resistance and stretching exercises | 5-30 minutes before and 10-35 minutes after each intervention. | Interference score of the Stroop test. Unit: millisecond. Smaller interference score means a better outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of Conflict-related neural activity between resistance and stretching exercises | 5-30 minutes before and 10-35 minutes after each intervention. | N2b (event-related potential) |
| Change of Neural activity related to locus coeruleus phasic response between resistance and stretching exercises | 5-30 minutes before and 10-35 minutes after each intervention. | P3 (event-related potential) |
Countries
Taiwan
Outcome results
None listed