Acute Compartment Syndrome
Conditions
Keywords
ACS, Tibial plateau fractures, Tibial shaft fractures
Brief summary
Acute compartment syndrome (ACS) is defined as a clinical entity originated from trauma or other conditions, and remains challenging to diagnose and treat effectively. Threre is the controversy in diagnosing, treating ACS. It was found that there was no criterion about the ACS, and result unnecessary osteotomy. The presence of clinical assessment (5P) always means the necrosis of muscles and was the most serious or irreversible stage of ACS. Besides pressure methods, the threshold of pressure identifying ACS was also controversial.
Interventions
if it was suspected with ACS, the fasciotomy was conducted. but if the blister observed, it means decreased conmpartment sydrome. therefore, the blister observed can avoid unnecessary fasciotomy to patients suspected with ACS
Sponsors
Study design
Eligibility
Inclusion criteria
* Fracture patients with Schatzker V and VI, * Who were older than eighteen years.
Exclusion criteria
* The
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blister skin immunochemistry and immunofluorescence analysis | through study completion, an average of 1 year | CK1, 5, 10, claudin 1, 2 and occludin as determined by immunochemistry analysis, and skin barrier proteins; claudin 1, 2 and occludin was determined by immunofluorescence analysis and qPCR. |
| union time | through study completion, an average of 1 year | The relative data was collected about union time |
| No non-anatomic gap or step (larger than 5 mm) | through study completion, an average of 1 year | The relative data was collected about complications |
| secondary loss of reduction | through study completion, an average of 1 year | The relative data was collected about complications |
| Deep venous thrombosis | through study completion, an average of 1 year | The relative data was collected about complications |
| superficial wound problems | through study completion, an average of 1 year | The relative data was collected about complications |
| injury mechanism | up to 1 weeks | The relative data was collected about injury mechanism such as high falling accident, traffic accident, fall from standing height,Crushing |
| the time when the blister appeared | up to 4 weeks | The relative data was collected about the time when the blister appeared after injury |
| time to reconstructive surgery | time to when the surgery was conducted after 2 weeks | The relative data was collected about time to reconstructive surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CK levels | through hospitalization completion, an average of 1 month | CK levels |
| chloride levels | through hospitalization completion, an average of 1 month | chloride levels |
| UREA levels | through hospitalization completion, an average of 1 month | UREA levels |
Other
| Measure | Time frame | Description |
|---|---|---|
| VAS scores | through study completion, an average of 1 year | visual analogue scale |
| LKS score | through study completion, an average of 1 year | Lysholm knee score |
Countries
China