Presentation, Clinical Course and Patterns of Myocardial Damage Due to Viral Myocarditis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04527835

Enrollment

Registered

2020-08-27

Start date

2020-10-01

Completion date

2021-03-01

Last updated

2020-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Viral Myocarditis

Brief summary

Presentation, Clinical Course and Patterns of Myocardial Damage due to Viral Myocarditis

Detailed description

1. Determine the pattern of myocarditis in hospitalized patients with acute HF within the last 3 months. 2. Determine the pattern of broad spectrum cardiotropic viruses in patients with acute HF within the last 3 months. These viruses like enteroviruses, adenoviruses and parvo B19 virus, HBV, HCV and Covid 19 virus due to its increased prevelance nowadays.

Interventions

DIAGNOSTIC_TESTELIZA, Extraction of nucleic acid ,Determination of viral genome by using PCR, Quantitative real-time PCR to assess viral load ,Immunohistochemistry analysis of EMB.

ELIZA, Extraction of nucleic acid ,Determination of viral genome by using PCR, Quantitative real-time PCR to assess viral load ,Immunohistochemistry analysis of EMB.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

All patients admitted with symptoms , signs and echocardiographic finding suggesting myocarditis within 3 months from start of the symptoms. as acute heart failure, arrhythmias, typical chest pain with ST segment deviation in ECG . dilated cardiomyopathy associated with normal Coronary Angiography, history of upper respiratory tract infection within the last 3 months.

Exclusion criteria

1. Patients with significant coronary artery disease. 2. Patient with family history suggesting familial DCMP 3. Critically ill patients. 4. Patients who refuse to do coronary angiography . . 5. Patients with severe valvular heart disease. 6. Pregnant women 7. Patients with raised renal chemistry. 8. Echocardiographic finding showing LVEDD more than 6.5cm

Design outcomes

Primary

Measure	Time frame	Description
Determine the pattern of myocarditis in hospitalized patients with acute HF within the last 3 months	6 months	All patients admitted with symptoms , signs and echocardiographic finding suggesting myocarditis within 3 months from start of the symptoms. as acute heart failure, arrhythmias, typical chest pain with ST segment deviation in ECG . dilated cardiomyopathy associated with normal Coronary Angiography, history of upper respiratory tract infection within the last 3 months. All will be investigated for determine the pattern of viral myocarditis in those patients

Secondary

Measure	Time frame	Description
determination of the caustive organism	6 months	1\. Determine the pattern of broad spectrum cardiotropic viruses in patients with acute HF within the last 3 months. These viruses like enteroviruses, adenoviruses and parvo B19 virus, HBV, HCV and Covid 19 virus due to its increased prevelance nowadays.

Countries

Egypt

Contacts

Primary ContactShery Asaad, Resident

drshosho31@yahoo.com01270992244

Backup ContactAmr yousif, professor

amryoussef111@aun.edu.eg01027355511

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026