Cystic Fibrosis
Conditions
Keywords
body composition, rehabilitation
Brief summary
The aim is to evaluate the impact of a 3-week lasting residential rehabilitation program for patients with cystic fibrosis on their nutritional status measured as BMI and body composition and pulmonary function.
Detailed description
Cystic fibrosis Patients following a residential rehabilitation program consisting of dietary adaptation, physical therapy for airway drainage and supervised inhalation therapy and physical activity for at least 3 weeks are asked to participate. Weight, height, body composition and pulmonary function will be measured at start and end of the program. Dietary intake during the program is calculated based on a 2 day weighed intake diary and physical activity will be measured with the SenseWear pro 3 armband.
Interventions
OTHERRehabilitation
During the rehabilitation program a multidisciplinary team, consisting of a pneumologist, dietician, psychologist, social worker and several physiotherapists, coach the cystic fibrosis patients. The physiotherapists help with autogenic drainage and aerosol therapy (2-3 times/day) and supervise physical activity (5, 1-hour lasting, training sessions/week: swimming 2, Fitness training 2, 1 session of choice). The dietician calculates basal and theoretical energy needs . A carbohydrate-rich snack before exercise, to improve exercise tolerance and a carbohydrate-protein-rich snack afterwards to improve recuperation is provided.
Sponsors
University Hospital, Ghent
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Cystic fibrosis * stay at the rehabilitation center for at least 3 consecutive weeks
Exclusion criteria
* steroid use * absence from the program for more than 2 consecutive days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| body composition change | day 0 and day 21 (start and end of the rehabilitation program) | Dual energy X-ray absorptiometry measured Fat mass index (kg/m\*2) |
| Body mass index change | day 0 and day 21 (start and end of the rehabilitation program) | calculated based on weight and height (kg/m\*2) converted in standard deviations |
| Weight change | day 0 and day 21 (start and end of the rehabilitation program) | Scale weighed weight (kg) converted in standard deviations of normal population of normal populations |
| pulmonary function change | day 0 and day 21 (start and end of the rehabilitation program) | forced expiratory volume in 1 second (% of normal) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical activity | Week 1 | SenseWear pro 3 armband measured physical activity |
| dietary intake | 2 days/week for 3 consecutive weeks | macronutrient intake measured based on 2 days/week weighed nutritional intake |
Countries
Belgium
Outcome results
None listed