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Case Fatalities in Hospitalised COVID-19 Patients in the UK

Case Fatalities in Hospitalised COVID-19 Patients in the UK: An ISARIC Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04527458
Enrollment
70000
Registered
2020-08-26
Start date
2020-02-24
Completion date
2020-08-02
Last updated
2020-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19

Keywords

COVID-19, ISARIC, Hospitalisations, Mortality, Case fatality, United Kingdom

Brief summary

This study will investigate how the case fatality in hospitalised patients with COVID-19 has changed throughout the pandemic. It will also explore possible mechanisms that could be driving these changes. This analysis will enhance our understanding of the virus, which will be important for researchers and clinicians to respond appropriately.

Interventions

OTHERPatient Characteristics

Characteristics of the patients

OTHERCOVID-19 treatments

Specific treatments used on COVID-19 patients

OTHERDifferences in triage

Triage criteria for treating COVID-19 patients

OTHERSurge capacity

Capacity of hospitals

Sponsors

International Severe Acute Respiratory and Emerging Infection Consortium
CollaboratorOTHER
BREATHE Health Data Research Hub
CollaboratorUNKNOWN
University of Edinburgh
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* All patients admitted with a proven or high likelihood of COVID-19

Design outcomes

Primary

MeasureTime frameDescription
Case fatality23 weeksThe proportion of new admissions with COVID-19 who died over time

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026