Fetal Ovarian Cyst
Conditions
Keywords
child, puberty
Brief summary
This study is based on pubertal surveillance of fetal ovarian cysts (KOF). Fetal ovarian cysts (KOF) detected during fetal ultrasound examinations occur during the 3rd trimester of pregnancy and are of unknown cause.
Detailed description
These cysts are functional in the vast majority of cases and are therefore likely to disappear spontaneously, but they may become complicated before regressing. Apart from complication, the natural evolution of these cysts, which are said to be simple because they are liquid on ultrasound, is towards regression in the first months of neo-natal life. Surveillance during the 1st year of life showed that simple cysts regressed during the 1st trimester. In the case of complicated cysts, oophorectomy was necessary in 9 cases. In the 1-year follow-up, the ovarian recovery rate was significantly different depending on the appearance of the cyst (p\<0.0001); 60 ovaries out of 89 homolateral to the cyst were follicular, of which 48/49 (98%) were carriers of fluid cysts and 12/40 (30%) were initially heterogeneous. The origin of these cysts is unknown, the ovary is again physiologically stimulated during the onset of puberty. No series in the literature gives the long-term ovarian prognosis for these patients. We wish to evaluate the pubertal evolutionary profile of patients followed at the University Hospital for KOF. The data collected concerning puberty (age of menses) will be examined in relation to the age of menses in the siblings and in the mother, as well as to the data in the literature on the age of the first menses in France.
Interventions
OTHERQuestionnaire
Pubertal course questionnaire
Sponsors
University Hospital, Toulouse
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
8 Years to 18 Years
Inclusion criteria
* Patients at least 8 years of age at the time of inclusion. * Patients being followed for fetal ovarian cyst. * Minor patients of whom at least one of the two holders of parental authority has given his or her non-opposition. * Patients covered by a social security scheme.
Exclusion criteria
* Patients less than 8 years of age at the time of inclusion * Ovarian cysts outside the neonatal period * Refusal to participate. * Opposition to disclosure of neonatal data. * Pregnant or nursing patient.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Age of onset of first menstruation | Day 1 | Age of onset of first menstruation defined with one decimal place (year and month). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ovarian volumes | Day 1 | Homo and contralateral ovarian volumes at the cyst. |
| Presence or not of follicles | Day 1 | Presence or not of follicles on both ovaries. |
| first menstruation description - age of breast onset | Day 1 | Age of breast onset |
| first menstruation description - cycle length | Day 1 | cycle length in the last three months |
| first menstruation description - cycle disorder | Day 1 | rate of patients with cycle disorder |
| first menstruation description dysmenorrhoea. | Day 1 | dysmenorrhoea. |
| Average age of maternal and sister rules | Day 1 | Average age of maternal and sister menstruation. |
| percentage of hyperandrogenism | Day 1 | Percentage of girls with clinical signs of hyperandrogenism or elevated testosterone levels. |
| Hormonal levels - AMH | Day 1 | AMH levels |
| Hormonal levels - LH | Day 1 | Luteinizing hormone (LH) levels |
| Hormonal levels - FSH | Day 1 | follicle stimulating hormone (FSH) levels |
| Hormonal levels - estradiol | Day 1 | estradiol levels |
| rate of ovarian cyst recurrence | Day 1 | Ovarian cyst recurrence rate |
| first menstruation description menorrhagia | Day 1 | menorrhagia |
Countries
France
Contacts
Primary ContactCatherine PIENKOWSKI, MD
Outcome results
None listed