Sleep Apnea Syndromes
Conditions
Keywords
apnoea hypopnoea index, CPAP
Brief summary
To date, no published systematic review and meta-analysis has compared AHI-CPAPflow and AHI-PSGgold. Therefore, the primary objective of this study is to compare published data for AHI-PSGgold and AHI-CPAPflow in patients treated by CPAP.
Detailed description
The secondary objectives are to evaluate, in a manner similar to the primary objective, data for apnoea indices (AI), hypopnoea indices (HI), respiratory disturbance indices (RDI) and respiratory effort related arousals (RERAs) and to perform subgroup analyses focusing on the inclusion/exclusion of central apnoea patients, BMI levels, CPAP device brands, pressure titration modes, use of a predetermined and fixed pressure level or not, and the impact of a 4%-PSG desaturation criteria versus 3%-PSG on index accuracy.
Interventions
DEVICEContinuous Positive Airway Pressure
Continuous Positive Airway Pressure device deployed for at least one night synchronously with polysomnography.
DEVICEPolysomnography
Polysomnography deployed for at least one night synchronously with Continuous Positive Airway Pressure.
Sponsors
University Hospital, Montpellier
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All (full scientific) study designs and publication types written in English and reporting Bland-Altman test results (or other tests suggesting the presence of the required data) between simultaneous, paired, polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data describing sleep disordered breathing.
Exclusion criteria
* Duplicates * Does not refer to a full scientific article (e.g. case reports are excluded). * Meta-analysis * Paediatric populations (populations \<18 years are excluded). * Absence of appropriate paired results: synchronized polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data must be reported for ≥1 of the following measures: Apnoea-Hypopnoea-Indices (AHI), Apnoea-Indices (AI), Hypopnoea-Indices(HI), respiratory disturbance index (RDI), respiratory effort related arousals (RERA). * Absence of appropriate test comparing paired results: the study must use ≥1 of the fol-lowing tests to compare the previously mentioned PSG-vs-CPAP-derived data: a bland-altman or correlation test, other conformity tests, tests of differences in centrality. * Inappropriate PSG scoring 1: PSG-derived variables must be coded following the American Academy of Sleep Medicine 2007 (or more recent) guidelines. * Inappropriate PSG scoring 2: PSG-derived variables must be scored manually. * Inappropriate PSG scoring 3: oxygen desaturation level used for scoring must be mentioned and at 3% or 4%. * Inappropriate CPAP description: brand/device names must be mentioned.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The mean difference between AHI-CPAPflow and AHI-PSGgold | Day 0 | AHI-CPAPflow = Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure AHI-PSGgold = Apnoea-Hypopnoea-Indices Determined by Polysomnography |
| The standard deviation for the mean difference between AHI-CPAPflow and AHI-PSGgold | Day 0 | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The mean difference between HI-CPAPflow and HI-PSGgold | Day 0 | HI-CPAPflow = Hypopnoea--Indices Determined Via Continuous Positive Airway Pressure HI-PSGgold = Hypopnoea--Indices Determined by Polysomnography |
| The standard deviation for the mean difference between HI-CPAPflow and HI-PSGgold | Day 0 | — |
| The mean difference between RDI-CPAPflow and RDI-PSGgold | Day 0 | RDI-CPAPflow = Respiratory Disturbance Indices Determined Via Continuous Positive Airway Pressure RDI-PSGgold = Respiratory Disturbance Indices Determined by Polysomnography |
| The mean difference between AI-CPAPflow and AI-PSGgold | Day 0 | AI-CPAPflow = Apnoea--Indices Determined Via Continuous Positive Airway Pressure AI-PSGgold = Apnoea--Indices Determined by Polysomnography |
| The mean difference between RERA-CPAPflow and RERA-PSGgold | Day 0 | RERA-CPAPflow = Respiratory Effort Related Arousals Determined Via Continuous Positive Airway Pressure RERA-PSGgold = Respiratory Effort Related Arousals Determined by Polysomnography |
| The standard deviation for the mean difference between RERA-CPAPflow and RERA-PSGgold | Day 0 | — |
| The standard deviation for the mean difference between RDI-CPAPflow and RDI-PSGgold | Day 0 | — |
| The standard deviation for the mean difference between AI-CPAPflow and AI-PSGgold | Day 0 | — |
Countries
France
Outcome results
None listed