Osteoporosis, Osteopenia, Sarcopenia
Conditions
Keywords
aerobic exercise, resistive exercise, balance, falling, physical performance, osteosarcopenia
Brief summary
The purpose of this study is to assess the efficacy of combination of aerobic and resistive exercise on activities of daily living and risk of fall in osteosarcopenic patients
Detailed description
After being informed about the study and potential risk, all patients giving written informed consent will undergo study entry. to begin with: assessment with bioelectrical body composition analyzer and first exercise and assessment clinical scales 1th month: assessment with bioelectrical body composition analyzer and assessment clinical scales 3th month: assessment with bioelectrical body composition analyzer and assessment clinical scales
Interventions
OTHERexercise
the combination of aerobic and resistive exercise, three time a week
Sponsors
Sisli Hamidiye Etfal Training and Research Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Female and male patients over 70 years of age followed-up from osteoporosis outpatient clinic
Eligibility
Sex/Gender
ALL
Age
70 Years to 91 Years
Healthy volunteers
Yes
Inclusion criteria
* Over 70 years of age * Clinical diagnosis of osteoporosis or osteopenia * Independent mobilization * Walking speed \< 0.8 m / sec * Grip strength \< 20 kg for women, \< 30 kg for men
Exclusion criteria
* Uncontrolled hypertension (systolic blood pressure\> 200 mmHg, diastolic blood pressure\> 110 mmHg) * Uncontrolled diabetes mellitus * Stroke, hip fracture, knee and hip arthroplasty, spinal surgery in the last 6 months * Severe cardiac arrhythmia * Myocardial infarction in the last 6 months * Severe dementia and difficulties in cooperation * Cardiac pacemaker * Dialysis * Acute infection * Severe edema * Malignancy patients * Severe anemia (Hgb \<8 mg / dl)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline on Skeletal Muscle Mass Measurement at month 3 | Baseline and Month 3 | Assessment with bioelectrical body composition analyzer male: SMI\<9,2 kg/m2 female: SMI\<7,4 kg/m2 |
| Change from Baseline on Skeletal Muscle Mass Measurement at month 1 | Baseline and Month 1 | Assessment with bioelectrical body composition analyzer male: SMI\<9,2 kg/m2 female: SMI\<7,4 kg/m2 |
| Change from Baseline on Katz Activities of Daily Living Scale at month 3 | Baseline and Month 3 | minimum 0, maximum 6, high scores: better |
| Change from Baseline on Katz Activities of Daily Living Scale at month 1 | Baseline and Month 1 | minimum 0, maximum 6, high scores: better |
| Change from Baseline on Short Physical Performance Battery at month 3 | Baseline and Month 3 | 0-low perfomance, 12-good performance |
| Change from Baseline on Short Physical Performance Battery at month 1 | Baseline and Month 1 | 0-low perfomance, 12-good performance |
| Change from Baseline on Berg Balance Test at month 3 | Baseline and Month 3 | maximum 56 point, a score of \< 45 indicates individuals may be at greater risk of falling. |
| Change from Baseline on Berg Balance Test at month 1 | Baseline and Month 1 | maximum 56 point, a score of \< 45 indicates individuals may be at greater risk of falling. |
| Change from Baseline on Timed Up and Go Test at month 3 | Baseline and Month 3 | Stand up and walk 3 meters, turn around, walks back to the chair and sit down.14 seconds or longer : high risk for falling |
| Change from Baseline on Timed Up and Go Test at month 1 | Baseline and Month 1 | Stand up and walk 3 meters, turn around, walks back to the chair and sit down.14 seconds or longer : high risk for falling |
| Change from Baseline on Five Times Sit to Stand Test at month 3 | Baseline and Month 3 | Lower times: better scores |
| Change from Baseline on Five Times Sit to Stand Test at month 1 | Baseline and Month 1 | Lower times: better scores |
Countries
Turkey (Türkiye)
Outcome results
None listed