Bruise, Contusion
Conditions
Brief summary
Subjects will have a mechanically induced bruise photographed over a period of 11 days to record the healing process. Assessors will rate the bruises to develop a bruising scale.
Detailed description
Observational study. Healthy normal volunteers will come into the clinic and have a bruise induced. The bruised area will be photographed each day through Day 11. Images will be provided to the Validator Team to rate on a 0-5 scale of severity. The actual numbers of volunteers will be adjusted to ensure there are at least 15 images for each Grade. The clinical site will be provided photography equipment, and study staff will be trained on photography technique to standardize the image quality and resolution across the study. The Validator Team will review the images and categorize them in to Grades 0-5.
Interventions
None listed
Sponsors
Cearna, Inc.
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Fitzpatrick skin type 1-3 * BMI 25 kg/m2 * Self described bruisers * Intact skin in the target area, free of markings, blemishes and hair
Exclusion criteria
* Use of recreational drugs, steroids, pain medications, other homeopathic remedies, anticoagulant therapies, antiplatelet therapy * Known history of dermal sensitivity, serious illness, hematological abnormality, impaired wound healing * Inability to forego application of topical products in the target area * Hair removal by laser, wax or chemicals within one week prior to Day 1 * Avoid tanning beds * Active wound or infection in the target area * History of keloids or hypertrophic scarring * History of collagen or vascular disease * History of organ transplant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bruise Healing over time | 11 days | Record bruise images over 11 days |
Countries
United States
Outcome results
None listed