Exploring Risk Assessment and Recovery From COVID-19 Infection in Hospitalised Patients
Conditions
Brief summary
A novel coronavirus, designated corona virus disease 2019 (COVID-19) has resulted in a Pandemic at the time of writing (27th April) the reported number of confirmed cases exceeding 3 million and over 200000 associated deaths. The burden on global critical care has been considerable. As of 24th April there have been 8752 UK critical care admissions with services under considerable strain, and a mortality rate over 50%. Survivors of critical illness will require significant input. This study will perform mixed methods to provide rich data on risk stratification and recovery from critical illness. Recovery from a novel disease requires documenting and the study reports physical and psychological changes following hospital discharge in survivors. In addition qualitative interviews are being conducted with patients who have survived and been discharged from critical care along with their relatives and treating professionals, to better understand their needs during recovery.
Interventions
None listed
Sponsors
Western Sussex Hospitals NHS Trust
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Adults ≥18 years admitted to ICU with SARS-CoV-2 and survived 2. Relatives or friends and professionals involved in the care of these patients.
Exclusion criteria
1. Patients \<18 years; 2. Patients with a negative test for SARS-CoV-2 or patients not tested due to absence of symptoms;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physical | through study completion , an average of 1 year | Chelsea critical care physical assessment tool |
| Health Related Quality of life | at 3 months | Short Form Survey on health related quality of life (SF-12). Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations). The United States population average PCS-12 and MCS-12 are both 50 points. Higher scores indicate better outcome. |
| Psychological | through study completion , an average of 1 year | Depression Test Questionnaire (PHQ-9). Scores range from 1 to 27 and higher scores indicate worse outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| risk stratification | through study completion and average of 1 year | escalation to critical care (Yes/No) |
Countries
United Kingdom
Outcome results
None listed