Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration

Conditions

Atherosclerosis

Brief summary

The purpose of this collaboration is to establish a multi-modality image database including coronary angiograms, optical coherence tomography (OCT), computed tomography angiograms (CTA) and cardiac magnetic resonance imaging (CMR) for future studies. The main goal of this collaboration is to create a resource to promote further understanding of the pathobiology of atherosclerosis through image analysis.

Detailed description

The purpose of this collaboration is to establish a multi-modality image database including coronary angiograms, optical coherence tomography (OCT), computed tomography angiograms (CTA) and cardiac magnetic resonance imaging (CMR) for future studies. About one thousand patients who underwent coronary angiography with OCT and had a CTA prior to catheterization at Tsuchiura Kyodo General Hospital (TKGH) in Japan, will be included. A subset of these patients also had CMR. The main goal of this collaboration is to create a resource to promote further understanding of the pathobiology of atherosclerosis through image analysis.

Kinoshita D, Suzuki K, Fujimoto D, Niida T, Minami Y, Dey D, Lee H, McNulty I, Ako J, Ferencik M, Kakuta T, Jang IK.

2025-02-074 citations

10.1016/j.jcct.2025.01.010

Relationship Between Coronary Artery Calcium Score and Vulnerability of Culprit Plaque Assessed by OCT in Patients With Established Coronary Artery Disease

Daichi Fujimoto, Eisuke Usui, Rocco Vergallo, Daisuke Kinoshita, Keishi Suzuki et al. (15 authors)

Circulation Cardiovascular Imaging2024-12-203 citations

10.1161/circimaging.124.017099

Differences in total plaque burden between plaque rupture and plaque erosion: A combined computed tomography angiography and optical coherence tomography study.

Niida T, Usui E, Suzuki K, Kinoshita D, Yuki H, Fujimoto D, Covani M, Dey D, Lee H, McNulty I, Ferencik M, Yonetsu T, Kakuta T, Jang IK.

2024-09-241 citations

10.1016/j.jcct.2024.09.007

Relationship between plaque burden and plaque vulnerability: Acute coronary syndromes versus chronic coronary syndrome.

Kinoshita D, Suzuki K, Fujimoto D, Niida T, Usui E, Minami Y, Dey D, Lee H, McNulty I, Ako J, Ferencik M, Kakuta T, Jang IK.

2024-09-144 citations

10.1016/j.jcct.2024.09.002

Relationship Between Calcified Plaque Burden, Vascular Inflammation, and Plaque Vulnerability in Patients With Coronary Atherosclerosis.

Fujimoto D, Kinoshita D, Suzuki K, Niida T, Yuki H, McNulty I, Lee H, Otake H, Shite J, Ferencik M, Dey D, Kakuta T, Jang IK.

2024-09-0424 citations

10.1016/j.jcmg.2024.07.013

Level of Perivascular Inflammation Is Significantly Lower Around the Left Internal Mammary Artery Than Around Native Coronary Arteries

Haruhito Yuki, Thoralf M. Sundt, Takayuki Niida, Keishi Suzuki, Daisuke Kinoshita et al. (14 authors)

Journal of the American Heart Association2024-06-161 citations

10.1161/jaha.123.033224

Computed Tomography Angiography Characteristics of Thin‐Cap Fibroatheroma in Patients With Diabetes

Keishi Suzuki, Daisuke Kinoshita, Takayuki Niida, Haruhito Yuki, Daichi Fujimoto et al. (13 authors)

Journal of the American Heart Association2024-05-142 citations

10.1161/jaha.123.033639

Layered plaque is associated with high levels of vascular inflammation and vulnerability in patients with stable angina pectoris.

Niida T, Kinoshita D, Suzuki K, Yuki H, Fujimoto D, Dey D, Lee H, McNulty I, Ferencik M, Yonetsu T, Kakuta T, Jang IK.

2024-04-224 citations

10.1007/s11239-024-02982-3

Sex-Specific Association Between Perivascular Inflammation and Plaque Vulnerability

Daisuke Kinoshita, Keishi Suzuki, Haruhito Yuki, Takayuki Niida, Daichi Fujimoto et al. (13 authors)

Circulation Cardiovascular Imaging2024-02-0115 citations

10.1161/circimaging.123.016178

Higher Noncalcified Plaque Volume Is Associated With Increased Plaque Vulnerability and Vascular Inflammation

Keishi Suzuki, Daisuke Kinoshita, Haruhito Yuki, Takayuki Niida, Tomoyo Sugiyama et al. (16 authors)

Circulation Cardiovascular Imaging2024-01-0119 citations

10.1161/circimaging.123.015769

A novel deep learning model for a computed tomography diagnosis of coronary plaque erosion.

Park S, Yuki H, Niida T, Suzuki K, Kinoshita D, McNulty I, Broersen A, Dijkstra J, Lee H, Kakuta T, Ye JC, Jang IK.

2023-12-279 citations

10.1038/s41598-023-50483-9

Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes

Keishi Suzuki, Takayuki Niida, Haruhito Yuki, Daisuke Kinoshita, Daichi Fujimoto et al. (12 authors)

Journal of the American Heart Association2023-11-2812 citations

10.1161/jaha.123.031474

High-Risk Plaques on Coronary Computed Tomography Angiography: Correlation With Optical Coherence Tomography.

Kinoshita D, Suzuki K, Usui E, Hada M, Yuki H, Niida T, Minami Y, Lee H, McNulty I, Ako J, Ferencik M, Kakuta T, Jang IK.

2023-09-1326 citations

10.1016/j.jcmg.2023.08.005

Sex Differences in Coronary Atherosclerotic Phenotype and Healing Pattern on Optical Coherence Tomography Imaging

Lena Marie Seegers, Doreen DeFaria Yeh, Taishi Yonetsu, Tomoyo Sugiyama, Yoshiyasu Minami et al. (18 authors)

Circulation Cardiovascular Imaging2023-07-287 citations

10.1161/circimaging.123.015227

Coronary Inflammation and Plaque Vulnerability: A Coronary Computed Tomography and Optical Coherence Tomography Study

Haruhito Yuki, Tomoyo Sugiyama, Keishi Suzuki, Daisuke Kinoshita, Takayuki Niida et al. (13 authors)

Circulation Cardiovascular Imaging2023-03-0132 citations

10.1161/circimaging.122.014959

Level of Vascular Inflammation Is Higher in Acute Coronary Syndromes Compared with Chronic Coronary Disease

Makoto Araki, Tomoyo Sugiyama, Akihiro Nakajima, Taishi Yonetsu, Lena Marie Seegers et al. (13 authors)

Circulation Cardiovascular Imaging2022-11-0126 citations

10.1161/circimaging.122.014191

Plaque Rupture, Compared With Plaque Erosion, Is Associated With a Higher Level of Pancoronary Inflammation.

Nakajima A, Sugiyama T, Araki M, Seegers LM, Dey D, McNulty I, Lee H, Yonetsu T, Yasui Y, Teng Y, Nagamine T, Nakamura S, Achenbach S, Kakuta T, Jang IK.

2021-11-0857 citations

10.1016/j.jcmg.2021.10.014

Interventions

OTHEROptical Coherence Tomography (OCT) and Computed Tomography Angiography (CTA)

Subjects underwent CTA, then OCT during cardiac catheterization as part of their standard clinical care.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

No

Inclusion criteria

* Had CTA prior to cardiac catheterization and then OCT during catheterization

Exclusion criteria

\-

Design outcomes

Primary

Measure	Time frame	Description
Major Adverse Cardiac Events (MACE)	1 Year	MACE

Countries

Japan, United States

Outcome results

None listed