Cerebral Ischemia
Conditions
Keywords
Endovascular thrombectomy, acute ischaemic stroke, large-vessel occlusion
Brief summary
Endovascular thrombectomy is the standard of care for acute ischaemic stroke due to large-vessel occlusion. Current guidelines for periprocedural anaesthesiological care give gross recommendations on management of stroke patients during recanalization, but lack detailed information. To determine how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique, choice of substances, haemodynamic management, and ventilation. With a multivariate analysis, the investigators will look for the factors of anesthetic management that are independently correlated with a good or bad outcome.
Detailed description
see brief summary
Interventions
None listed
Sponsors
European Society of Anaesthesiology
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Endovascular stroke treatment involving anaesthesia care
Exclusion criteria
* In-hospital onset of stroke * Inclusion in an interventional study concerning the anaesthesia protocol * Age under 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neurological outcome 90 days after the stroke | 90 days | Neurological outcome is measured using the modified Rankin Scale \[0-6\], with higher values indicating worse outcome. As a Primary Outcome Measure, the scale will be dichotomized into good (modified Rankin Scale ≤ 2) versus poor (modified Rankin Scale \> 2) outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | 90 days | Mortality rate 90 days after the stroke. Mortality rate is the percentage of patients that have died within 90 days following their stroke. |
| Grade of recanalization | sixty minutes | Recanalization is classified according to the modified Thrombolysis in Cerebral Infarction classification (mTICI) \[0 - 3\], with higher values indicating better reperfusion. |
| Duration | 30 Minutes | Duration \[minutes\] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration \[minutes\] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration \[minutes\] from arterial puncture to end of endovascular thrombectomy. |
| Proportion of patients breathing spontaneously | sixty minutes | Proportion of patients breathing spontaneously after thrombectomy \[Time Frame: On transfer from angiography suite after thrombectomy, which typically takes 1 hour\]. This is defined as percentage of patients that breathe spontaneously without laryngeal mask, laryngeal tube, or endotracheal tube after thrombectomy. |
Countries
Germany
Contacts
Primary ContactAndreas Ranft, Dr.
Outcome results
None listed