Skip to content

Laparoscopic Hysterectomy With Prior Uterine Artery Ligation

Laparoscopic Hysterectomy With Prior Uterine Artery Ligation vs Conventional Laparoscopic Hysterectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04522232
Enrollment
127
Registered
2020-08-21
Start date
2017-12-01
Completion date
2020-05-31
Last updated
2022-10-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysterectomy, Uterine Artery Injury

Keywords

Hysterectomy, Laparoscopy, Uterine Artery Ligation

Brief summary

A randomized controlled trial was done on 127 women planned for TLH, and divided into two groups; group A includes women that underwent conventional TLH, and group B includes women that underwent TLH with prior uterine artery ligation at its origin. Both grouped were compared regarding the blood loss, operation time, intraoperative complications and post-operative follow-up.

Interventions

PROCEDUREconventional Total laparoscopic hysterectomy

the ascending branch of the uterine artery was identified close to the isthmus then ligated at this level, close to the uterus or coagulated, using bipolar diathermy. The utero-vesical fold was dissected and the bladder was pushed down done, thus moving the ureters laterally, which decreases the risk of including them in a suture. The vasculature of the uterus is now secured and this is evidenced by the pale color of the fundus. Using either bipolar diathermy or the harmonic ultracision, the cornual pedicles on one side were desiccated and cut. Also, both the uterosacral and cardinal ligaments were desiccated and cut. So that, the opposite side pedicles can be taken care of, the direction of manipulator was changed. The infundibulopelvic ligaments were desiccated and cut if it is necessary to remove both ovaries. A vaginal cuff was inserted into the vagina to identify the vault, which was then cut laparoscopically using a monopolar hook, where the specimen was completely detached.

PROCEDURETotal laparoscopic hysterectomy with prior uterine artery ligation at its origin

the uterine artery was dissected using the lateral approach; where dissection begins from the anterior leaf of the broad ligament. The triangle enclosed by the round ligament, external iliac artery, and infundibulopelvic ligament was opened. The areolar space was dissected and the origin of the uterine artery from the internal iliac and the ureter was identified. The uterine artery was then isolated from the surrounding structures and ligated by Hem-o-lok clips. then same steps as conventional Total laparoscopic hysterectomy

Sponsors

Helwan University
CollaboratorOTHER
Cairo University
CollaboratorOTHER
Al-Azhar University
CollaboratorOTHER
National Research Centre, Egypt
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
FEMALE
Age
40 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

any benign uterine pathology such as: * fibroid uterus * endometrial hyperplasia with failed hormonal therapy * DUB with failed medical and hormonal treatment * uterine prolapse.

Exclusion criteria

* gynecologic malignancy * presence of contraindications to laparoscopy.

Design outcomes

Primary

MeasureTime frameDescription
blood lossduring the LaparoscopyThe total blood loss was calculated from the suction apparatus. No irrigation was used throughout the surgery until the total blood loss was calculated. Peritoneal lavage was done with normal saline solution.
operation timeduring the Laparoscopystart time is the insertion of 10 mm telescope trocar end-time is the removal of all trocars

Secondary

MeasureTime frameDescription
intraoperative or postoperative complicationsduring the Laparoscopy and during the hospital stay (24 hours postoperative)intraoperative complications are that during the Laparoscopy postoperative complications are that during the hospital stay (24 hours postoperative)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026