Pathogen Detection in Infectious Uveitis

Pathogen Detection in Infectious Uveitis in China

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04521673

Enrollment

100

Registered

2020-08-20

Start date

2025-02-26

Completion date

2026-12-31

Last updated

2026-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious Iridocyclitis, Infectious Panuveitis

Keywords

infectious uveitis, pathogen, PCR

Brief summary

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection.Current study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection.

Detailed description

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection. The study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection, including multiple molecular bio-techniques. We also plan to explore the distribution of pathogens in infectious uveitis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Patient at a referal hospital eye clinic with clinically suspected infectious uveitis

Exclusion criteria

* Patients not eligible for the Inclusion Criteria * Confirmed auto-immune uveitis

Design outcomes

Primary

Measure	Time frame	Description
Prevalence and distribution of intraocular infections in the study group	Oct 2020 to Sep 2022	Prevalence and distribution of intraocular infections in the study group

Secondary

Measure	Time frame	Description
The sensitivity and specificity of multiple molecular diagnostic methods for detection of bacteria or virus fungi in the study group	Oct 2020 to Sep 2022	The sensitivity and specificity of multiple molecular diagnostic methods for detection of bacteria or virus fungi in the study group

Countries

China

Contacts

CONTACTPing Fei, MD,PhD

shirleypingfei@126.com86-13636342098

PRINCIPAL_INVESTIGATORPing Fei, MD，PhD

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Outcome results