Chronic Obstructive Pulmonary Disease, Respiratory Failure
Conditions
Brief summary
High-flow nasal cannula (HFNC) is a device that delivers10 to 70 L min-1 of heated, humidified 100% oxygen via nasal route. It provides positive airway pressure, decreases dyspnea, decreases the work of breathing, and improves comfort
Detailed description
Beneficial effects of the HFNC system have been assessed based on 3 physiologic conditions: decreased dead space, a high concentration of inspiratory oxygen, and positive pressure in the oro-laryngeal cavity.Studies have shown that it improves oxygenation in various perioperative settings such as the apneic patients, patients with respiratory failure , and patients undergoing bronchoscopy
Interventions
COMBINATION_PRODUCTHigh flow nasal cannula
using sedation with the HFNC F&P AIRVOTM 2 to maintain oxygenation
COMBINATION_PRODUCTCONTROL
using general anaesthesia with one lung ventilation (OLV) technique
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* ASA physical status II and III, * undergoing VATS
Exclusion criteria
* refusal of patients * extrem of age
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| arterial partial pressures of oxygen | two hours | an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation. |
| pH measurement | two hours | an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation. |
Countries
Egypt
Contacts
Primary ContactRehab A. Abd Elaziz, Ass. Prof.
Outcome results
None listed