Remote Magnetic Versus Manual Navigation-guided Ablation for Non-outflow Tract Premature Ventricular Contractions: a Prospective, Randomized, Controlled Trial

Department of Cardiology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04519112

Enrollment

200

Registered

2020-08-19

Start date

2020-10-01

Completion date

2023-09-30

Last updated

2020-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature Ventricular Contraction

Brief summary

This prospective, randomized, controlled trial is designed to compare the safety and efficacy of remote magnetic navigation-guided ablation for ventricular premature complexes arising from non-outflow tracts with manual control navigation.

Interventions

PROCEDURECatheter Ablation

Catheter Ablation with RMN and MCN

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

1. non-outflow tract PVCs 2. Holter\>10,000/24h or PVCs load\>10% 3. the first ablation procedure 4. failure of at least one AAD to treat PVCs before ablation

Exclusion criteria

1. PVC ablation history 2. HF with NYHA IV 3. 3 months prior to AMI or PCI 4. Cardiac thrombosi 5. Hyperthyroidism 6. Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Freedom rate of PVC	one year	Efficacy endpoint
Procedure-related Complications	one year	Safety endpoint

Secondary

Measure	Time frame
fluoroscopic time	one day
ablation time	one day
procedure time	one day

Contacts

Primary ContactQi Jin, MD

jinqi127@163.com+8613020144766

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026