Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins

Clinical Outcomes of Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins: A Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04518176

Enrollment

400

Registered

2020-08-19

Start date

2020-09-01

Completion date

2022-08-31

Last updated

2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section Complications

Brief summary

Objective to assess the effectiveness of prophylactic bilateral uterine artery ligation (BUAL) in reducing the incidence of postpartum hemorrhage during cesarean delivery among women with twin pregnancy

Detailed description

A randomized clinical trial at Aswan University Maternity Hospital, Egypt. Women with twin pregnancy undergoing scheduled or emergency cesarean were randomized into two groups. In the BUAL group, women underwent BUAL before placental delivery; in the control group, women had cesarean delivery without BUAL. The primary outcome was the estimated blood loss during a cesarean

Interventions

PROCEDUREbilateral uterine artery ligation

The peritoneum over the vesico-uterine pouch already being incised horizontally, the peritoneum over the uterine isthmus and cervix was dissected downwards, and this dissection was then extended laterally

DRUGOxytocin

20 units by slow intravenous drip injection

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Masking description

open label randomized controlled study

Intervention model description

randomized controlled study

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* women undergoing cesarean section * twin pregnancy

Exclusion criteria

* Placenta previa. * Ante-partum hemorrhage. * patient refuse to participate

Design outcomes

Primary

Measure	Time frame	Description
mean Blood loss after placental separation	30 minutes	by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set

Secondary

Measure	Time frame	Description
Number of Participants with postpartum hemorrhage	12 hours	number pf participants with blood loss \> 1000ml
The number of participant needed for blood transfusion	24 hours	Calculation of the number of participant needed for blood transfusion

Countries

Egypt

Contacts

Primary Contacthany f Sallam, md

hany.farouk@aswu.edu.eg+20102435461

Backup Contactnahla w Shady, md

hanygyne@yahoo.com+201022336052

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026