Chronic Heart Failure, Chronic Kidney Diseases
Conditions
Keywords
Chronic cardio-renal syndrome biomarkers
Brief summary
The study is observational, prospective, including patients undergoing CRT-D / CRT-P implantation in the department of cardiology. In the current project, the researchers assumed that the improvement in cardiac function obtained in patients qualified according to the ESC / PTK guidelines for resynchronization therapy may improve renal function in a prospective 12-month follow-up. In addition, it is planned to take into account the possibility of temporary deterioration of kidney function, which may occur immediately after implantation of the resynchronization device due to the nephrotoxic effect of the contrast agent.
Interventions
DEVICEcardiac resynchronisation therapy (CRT) implantation
In a group of 100 patients with chronic cardio-renal syndrome, the blood and urine biomarkers are tested before CRT implantation and after 48 hours, 3 months and 1 year of follow-up.
Sponsors
University of Rzeszow
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
Adult patients with heart failure who had met the criteria for CRT implantation according to European Society of Cardiology guidelines for the treatment of heart failure
Exclusion criteria
* no written consent to participate in the study * no indications for CR implantation * current infection * children * pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of changes renal function: 48 hours, one month and one year after cardiac resynchronization therapy device implantation procedure. | 1 year for each patient in the study | Assessment of the number of patients with with chronic type 2 cardio-renal syndrome with improvement or deterioration renal function assessed by blood and urine biomarkers within the first 48 hours, one month and one year after CRT implantation. |
Outcome results
None listed