Multicentric Breast Cancer
Conditions
Keywords
multicentric, breast, cancer
Brief summary
The aim of this study is to determine if microRNA's have role in predicting multicentricity in breast cancer. If a specific microRNA will be found to be related with multicentricity, it will help us to make appropriate decisions on the treatment of patients with multicentric breast cancer.
Detailed description
In the study that will be held at Bezmialem Vakif University Medical Faculty, General Surgery Department, 20 unifocal and 20 multifocal breast cancer patients will be included. Tissues will be taken from both tumoral and normal breast tissues and they will be saved in microRNA later solution under -80°C. Then, 84 microRNA's will be studied in these tissues to see if they express any of these microRNA's.
Interventions
GENETICmiRNA
miRNA's expressed in breast cancer
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. Having breast cancer 2. Having no other malignancy 3. Female patient
Exclusion criteria
1. Having other malignancy 2. Under 18 years old 3. Male patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MicroRNA's in multicentric breast cancer | April 2014 | Evaluation of 84 microRNA's in patients with multicentric breast cancer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Treatment plan according to the detected microRNA in patients with multicentric breast cancer | April 2014 | If a specific microRNA will be detected in patients with multicentric breast cancer, treatment plan will be individualized according to the detected microRNA |
Countries
Turkey (Türkiye)
Outcome results
None listed