Effects of Video-Assisted Surgery on Ventilatory Parameters

Effects of Pneumoperitoneum on Ventilatory Parameters in Patients Undergoing Video-assisted Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04513262

Enrollment

Registered

2020-08-14

Start date

2015-03-20

Completion date

2018-11-10

Last updated

2020-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery--Complications

Brief summary

The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery. The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion

Interventions

PROCEDUREmechanical ventilation during video-assisted surgery

observed variation of ventilatory parameters during video-assisted surgery

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients who underwent video-assisted surgery by either classic laparoscopy or robotic-assisted surgery.

Exclusion criteria

* refusal to participate * conversion of surgery to laparotomy * need of vasopressure support * preoperative severe respiratory dysfunction

Design outcomes

Primary

Measure	Time frame	Description
lung compliance	one-hour and two-hours after induction of pneumoperitoneum	change in lung compliance (mL/cmH2O) before and after induction of pneumoperitoneum in patients undergoing VAS. Lung compliance is automatically calculated by the anesthesia machine during surgery. The study compares the magnitude in change associated with VAS.

Secondary

Measure	Time frame	Description
arterial to end-tidal CO2 difference	one-hour and two-hours after induction of pneumoperitoneum	difference in arterial to end-tidal CO2 (mmHg) during surgery. Arterial blood samples and end-tidal CO2 were simultanously obtained at the specific time-points.

Countries

Romania

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026