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CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients

CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04512118
Enrollment
22
Registered
2020-08-13
Start date
2020-03-15
Completion date
2020-07-30
Last updated
2026-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Presence of COVID-19 Compatible CT Abnormalities

Keywords

COVID19, 18F FDG PET, lung infection, CT, seriological tests

Brief summary

CT signs that are evocative of lung COVID-19 infections have been extensively described, whereas 18F-FDG-PET signs have not. Our current study aimed to identify specific COVID-19 18F-FDG-PET signs in patients that were (i) suspected to have a lung infection based on 18F-FDG-PET/CT recorded during the COVID-19 outbreak and (ii) whose COVID-19 diagnosis was definitely established or excluded by appropriate viral testing.

Interventions

DIAGNOSTIC_TESTPET-CT of 18F-FDG

Whole-body 18F-FDG-PET/CT was performed on a digital hybrid system (Vereos, Philips®)

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Patient coming to nuclear medicine for 18F-flurodesoxyglucose (FDG) positron emission tomography computed tomography (PET-CT) with suspicion of lung involvement * patient affiliated to a social security scheme or equivalent * adult patient having been informed of the study

Exclusion criteria

* patient with a negative covid 19 test

Design outcomes

Primary

MeasureTime frameDescription
Visual analysis of pulmonary lobes1 dayVisual analysis of the pulmonary lobes by calculating a extent score for each patient

Secondary

MeasureTime frameDescription
Measurement of metabolic activity1 dayMeasurement of metabolic activity with SUV max of lung areas with CT abnormalities

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 26, 2026