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CytoSorb in Patients With Liver Failure

Effects of Renal Replacement Therapy With Hemoadsoption in Patients With Liver Failure

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04511507
Enrollment
35
Registered
2020-08-13
Start date
2016-02-10
Completion date
2021-08-30
Last updated
2021-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Dysfunction

Brief summary

Hemoadsorption has been demonstrated to improve liver functional tests in patients with liver failure. The present study investigates the effects of three consecutive sessions of hemoadsorption, performed in accordance to the local protocol for treating patients with acute liver failure, on liver functional tests, severity scores and 30-days mortality. Paraclinical results and severity scores were obtained before and after the three consecutive sessions.

Interventions

three consecutive sessions of hemoadsorption in patients with liver failure

Sponsors

Institutul Clinic Fundeni
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients with acute liver failure or acute on chronic liver failure who require hemoadsorption in accordance with local guidelines

Exclusion criteria

* unsigned informed consent * duration of therapy under 12 hours * death before the three consecutive sessions

Design outcomes

Primary

MeasureTime frameDescription
30 days mortality30 days30 days mortality

Countries

Romania

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026