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Resistance Training and Milk Supplementation

Effects of High-protein Milk Supplementation on Muscular Strength and Power, Body Composition, and Skeletal Muscle Regulatory Markers Following Heavy Resistance Training in Resistance-trained Men

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04509297
Enrollment
30
Registered
2020-08-12
Start date
2018-01-04
Completion date
2018-05-05
Last updated
2020-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscular Hypertrophy

Keywords

Hypertrophy, body composition, milk, resistance training

Brief summary

Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains. The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers, hormonal responses and body composition in resistance-trained men.

Detailed description

The aim of this investigation was to compare the effects of high protein milk supplementation (daily and after training sessions) during 6 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to: To investigate the extent to which high protein milk supplementation will improve anabolic factors, lean body mass, fat mass and decrease catabolic markers after 6 weeks of resistance training in resistance-trained men.

Interventions

DIETARY_SUPPLEMENThigh protein milk

This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

DIETARY_SUPPLEMENTPlacebo

This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Sponsors

University of Tehran
CollaboratorOTHER
Marymount University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Aged 18-35 years of age * Healthy Males * Experienced at resistance training (at least 1 year of prior structured resistance training 3 x week).

Exclusion criteria

* smoking * chronic alcohol consumption * having any medical issues and diseases * lactose intolerance * the consumption of any dietary supplements (including vitamins or protein supplements) or medications for 6 months prior to participation

Design outcomes

Primary

MeasureTime frameDescription
Circulatory Myokines levels6 weeksFasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentration of myostatin and follistatin.
Circulatory hormone levels6 weeksFasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentrations of testosterone, IGF-1, growth hormone, insulin and cortisol
Body composition6 weeksLean body mass and body fatness will be evaluated using bioelectrical impedance

Secondary

MeasureTime frameDescription
Muscular Strength6 weeksUsing a 1 repetition maximum test (defined as the maximal weight an individual can lift for only one repetition) for the bench press and back squat exercises
Muscular Power6 weeksUsing the Wingate test

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026