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Effects of Combined Interventions to Optimize Recovery During High-intensity Exercises in Healthy Adults

Effects of Combined Interventions to Optimize Recovery During High-intensity Exercises in Healthy Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04508738
Enrollment
16
Registered
2020-08-11
Start date
2020-09-10
Completion date
2021-06-30
Last updated
2021-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The objective of the study is to evaluate the effects a complex recovery intervention during the breaks of a repeated sprint test on exercise performance compared to placebo and control conditions. The enhanced recovery package (ERP) includes neck cooling with an iced gel pad, drinking a 6% CHO solution, mouth-rinsing with a 10% CHO, 6 mg・kg -1 caffeine solution, performing submaximal squats and hyperventilating a hyperoxic mixture; all applied in each 3-min break in-between the six 30-s sprints. This intervention will be compared to a placebo and a control condition.

Interventions

OTHERERP

The ERP intervention is applied in a randomized and counter-balanced order across visits 2-4 in each 3-min break in-between the six 30-s sprints, with one intervention per visit. The order and timing of the constituents of the interventions will be strictly constant within and between participants. ERP: 1) neck cooling with an iced gel pad, 2) drinking a ∼ 6% CHO solution, 3) mouth-rinsing with a ∼10% CHO, ∼6 mg ・ kg -1 caffeine solution, 4) performing submaximal squats and 5) hyperventilating a hyperoxic mixture

OTHERPlacebo

The control intervention is applied in a randomized and counter-balanced order across visits 2-4 in each 3-min break in-between the six 30-s sprints, with one intervention per visit. The order and timing of the constituents of the interventions will be strictly constant within and between participants. 1\) neck cooling with room temperature gel pack, 2) drinking an artificially sweetened solution, 3) mouth-rinsing with artificially sweetened solution (containing no caffeine), 4) performing unloaded squat manoeuvres, 5) deep breaths with room air

Sponsors

Swiss Federal Institute of Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Subject)

Masking description

Participants will be blinded about the true nature of the placebo intervention

Intervention model description

Each participant will be tested on 4 different days with a control, a placebo and an interventional condition in random order.

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Informed Consent as documented by signature (Appendix Informed Consent Form) * Healthy * Male * Age: 18-40 years * Body-Mass-Index (BMI): 18.5-24.9 kg・m-2 * Trained individuals: max. Power output ≥ 4.0 Watts・kg-1 * Non-smoking * Willingness to adhere to the study rules

Exclusion criteria

* Known or suspected non-compliance, drug or alcohol abuse * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participants * Previous enrolment into the current study * Intake of medications affecting performance or the respiratory, cardiovascular or neuromuscular system * Acute or chronic illness affecting performance or the respiratory, cardiovascular or neuromuscular system

Design outcomes

Primary

MeasureTime frameDescription
Change in mean power outputthrough study completion, an expected average of 3 weeks per participantMeasured over the six 30s high-intensity cycling sprints in each of the three conditions. Mean power mirrors the body's ability to generate muscle power and physical energy. Any meaningful effects of the recovery interventions will eventually translate into a higher power output.
Change in fatigue indexthrough study completion, an expected average of 3 weeks per participantFatigue index = drop in power output from the beginning to the end a 30s sprint test. The change in this index will be calculated from the 1st to the 6th sprint test in each condition.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026