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Persistent Postoperative Pain After Major Emergency Abdominal Surgery

Persistent Postoperative Pain After Major Emergency Abdominal Surgery

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04508465
Enrollment
110
Registered
2020-08-11
Start date
2020-06-04
Completion date
2021-06-04
Last updated
2020-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Postoperative Pain

Brief summary

Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake, reduced pulmonary capacity and increased risk of complications and length of hospitalization. The literature does not supply much information on short- or longer-term outcomes of pain treatment for emergency surgery. The investigators know that for planned surgery in general around 10-50 percentage suffer from persistent postoperative pain. It is therefore important to follow-up on the longer-term outcomes after the standardized analgesic pain treatment. Based on a predefined patient group called OMEGA (Optimizing Major EMergency Abdominal surgery) the investigators hypothesize that OMEGA patients will present a significant incidence rate of patients with persistent postoperative pain and/or continued opioid/non-opioid usage. Therefore this study is to investigate the incidence of prolonged postoperative pain and opioid/non-opioid consumption in OMEGA patients at 3 month after major emergency abdominal surgery.

Interventions

None listed

Sponsors

Zealand University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* OMEGA patients (patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction) * Age 18 or more * Surgery performed within 72 hours of an acute admission or as an acute re-operation

Exclusion criteria

* Elective laparoscopy * Diagnostic laparotomy/laparoscopy where no subsequent procedure is performed * Non-elective hernia repair without bowel resection * Admission or transfer to an intensive care unit

Design outcomes

Primary

MeasureTime frameDescription
Pain MobilizationData is collected 3 months postoperativePain during mobilization last week based on a self-made questionary
OpioidsData is collected 3 months postoperativeDaily opioid usage last week based on a self-made questionary

Secondary

MeasureTime frameDescription
Barthel-20 IndexData is collected 3 months postoperativeSimple function measurement based on daily living Simple function measurement
Pain RestData is collected 3 months postoperativePain in rest last week based on a self-made questionary
Montreal Cognitive Assessment test (Mini-MoCA)Data is collected 3 months postoperativeCognitive function
EuroQol-5Data is collected 3 months postoperativeHealth related quality of life
Non-opiod AnalgesicData is collected 3 months postoperativeNon-opioid analgesic usage based on a self-made questionary

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026