Bowel Dysfunction
Conditions
Brief summary
Dysfunction and intestinal endocrine dysfunction. This project will use genomics, metabonomics, microbiome and other omics techniques to study the clinical pathway of CID integrated therapy.
Interventions
DRUGNutritional Therapy, Metabolic Disorder, Regular
According to the result reported by Byrne, Wilmore, etc. in 1992 \ 1995, the use of growth hormone, glutamine, modified diet and other measures proposed intestinal rehabilitation treatment. Then, check the patient's quality of life survey, nutritional status, inflammation indicators and other changes every three months, and use metabolomics and microbiomic tools to detect changes in the patient's nutritional metabolism, intestinal microecology, etc., and adjust the patient's nutritional treatment and microecological treatment based on the results Program.
Sponsors
Nanjing University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Intervention model description
Intestinal dysfunction is defined as the damage of intestinal substance and/or function, which leads to digestion, absorption and/or mucosal barrier function.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* The Patients with chronic bowel dysfunction
Exclusion criteria
* Past severe underlying diseases of the respiratory system and cardiovascular system, * Allergy to treatment-related drugs, * Pregnancy, * Accept CID surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nutrition index | 3 years |
Outcome results
None listed