Chronic Intestinal Pseudo-obstruction, Constipation, Eosinophilic Esophagitis, Fecal Incontinence, Functional Vomiting, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Irritable Bowel Syndrome (IBS), Small Intestinal Bacterial Overgrowth
Conditions
Keywords
Eosinophilic esophagitis, Chronic intestinal pseudo-obstruction, Small Bowel dysmotility, SIBO, Vomiting, Functional dyspepsia, Functional bloating, Gastroparesis
Brief summary
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions. It will also help in promoting future research in gastroenterology motility disorders
Detailed description
Develop a registry (list of patients) of patients seen the clinics with motility disorders. Motility diagnosis based on billing diagnostic codes are not accurate. Motility diagnosis will be made by physicians with specialized in GI Motility, based on clinical consensus of diagnostic criteria. The information gathered from the database will be used to help promote future clinical research in the GI motility and Neurogastroenterology Unit at Indiana University School of Medicine. Gastrointestinal motility symptoms are very common. It encompasses a wide range of problems, such as dysphagia, heartburn, nausea, emesis, food regurgitation, abdominal distension, weight loss, postprandial bloating, constipation, and diarrhea. An accurate diagnosis is essential in order to promote cost-effective treatment and future research to benefit patients with GI motility disorders Specific Aims 1. Primary Aim: Identification of patients by accurate motility diagnosis 2. Secondary Aims: 1. To develop Patient Reported Outcome (PRO) measurements in patients with small intestinal bacterial overgrowth (SIBO) 2. To develop Patient Reported Outcome (PRO) measurements in patients with gastroparesis
Interventions
OTHERno intervention
Sponsors
Indiana University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Patients who presented to the GI outpatient clinics, in-patient consult service, and outpatient endoscopy centers within the Division of Gastroenterology and Hepatology 2. Carries a diagnosis of GI motility disorder based on the diagnostic criteria listed in table
Exclusion criteria
1\. Coexisting medical conditions that may limiting participation in clinical research trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identification of patients by accurate motility diagnosis | .through study completion, an average of 10 years | Motility diagnosis will be made by physicians with specialized in GI Motility, based on consensus diagnostic criteria. The information gathered from the database will be used to help promote future clinical development and research in GI motility disorders. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient Reported Outcome (PRO) Measurements in Patients with Small Intestinal Bacterial Overgrowth (SIBO) | through study completion, an average of 10 years | SIBO-disease specific patient questionnaire will be compared between patients with aerodigestive tract SIBO and coliform SIBO |
| Patient Reported Outcome (PRO) Measurements in Patients with Gastroparesis | through study completion, an average of 10 years | Patient Assessment of GI - Symptom (PAGI-SYM) scores will be compared between patients with emesis-predominant, dyspeptic-predominant, and regurgitation-predominant gastroparesis. |
Countries
United States
Contacts
CONTACTLainna Cohen
CONTACTMaureen Schilling
PRINCIPAL_INVESTIGATORJohn m Wo, MD
Indiana University
Outcome results
None listed