Comparison of Postoperative Wound Between Dermabond Prineo(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and Subcuticular Suture in Simultaneous Total Knee Arthroplasty

Comparison of Postoperative Wound Between Dermabond PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and Subcuticular Suture in Simultaneous Total Knee Arthroplasty

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04506580

Enrollment

Registered

2020-08-10

Start date

2019-03-06

Completion date

2020-07-30

Last updated

2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Knee Cutaneous Suture, Dermabond, Subcuticular Suture

Brief summary

This study aims to compare the clinical results of postoperative wound between Dermabond PRINEO™(2-octyl Cyanoacrylate adhesive and polyester mesh) and subcuticular suture in simultaneous total knee arthroplasty There is previous studies over whether or not to use skin adhesive material is superior or inferior to subcuticular suture This study prospectively randomized patients receiving bilateral total knee arthroplasty(TKA). Patients preference and clinical results was investigated in both knee of same patients who received skin adhesive or subcuticular suture in each knee.

Interventions

PROCEDUREDERMABOND™ PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) vs subcuticular nylon suture

DERMABOND™ PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and subcuticular nylon suture are applied for each knee

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Masking description

Double blind

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients for total knee arthroplasty * having medicare insurance

Exclusion criteria

* Rheumatoid arthritis * Other inflammatory arthritis * Neuropsychiatric patients * Allergy or intolerance to study material * Patients with an American Society of Anesthesiologists(ASA) score of IV (angina, congestive heart failure, dementia, cerebrovascular accident)

Design outcomes

Primary

Measure	Time frame	Description
wound Hypertrophy scale at postoperative 6 month	at postoperative 6 months	Vancouver scar scale, patient and observer report scar assessment scale

Secondary

Measure	Time frame	Description
Skin closure time	operation day	Skin closure time for each group
wound complication	postoperative 2 weeks	—
Stitch out time	postoperative 2 weeks	—
Stitch out visual visual analogue scale(VAS)	postoperative 2 weeks	VAS range from 1 to 10 ( 1means minimal pain 10 means maximal pain)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026