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Comparison of Early Outcomes of Minimally Invasive Surgery for Oesophageal Replacement Versus Open Surgery in Children

Comparison of Early Outcomes of Minimally Invasive Surgery for Oesophageal Replacement Versus Open Surgery in Children

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04504656
Enrollment
20
Registered
2020-08-07
Start date
2020-03-01
Completion date
2022-10-01
Last updated
2020-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anastomosis; Complications, Post-Op Complication

Brief summary

a comparative prospective study of postoperative between minimally invasive and open surgery complications for esophageal replacement in children

Detailed description

Esophageal replacement in childhood is indicated in esophageal atresia patients with long-gap defects or following complications of primary esophageal anastomosis, as well as in patients with trauma and scarring to the esophagus following caustic ingestion. It is widely accepted that the ideal esophageal replacement is one that resembles the function of the native esophagus with minimal deterioration over time. Several techniques of esophageal replacement have been developed. These have focused mainly on the use of native tissues (including the stomach, jejunum, and colon) as conduits (1), attempts to use a synthetic prosthesis have been largely unsuccessful. In an attempt to reduce the trauma and morbidity associated with laparotomy and thoracotomy incisions, minimally invasive techniques are increasingly used. (2-4). Meta-analyses of adult esophagectomy for the treatment of esophageal cancer support the use of minimally invasive surgery (5) however, equivalent comparative studies in the pediatric population are lacking. As such, it is unclear whether minimally esophageal replacement is as safe as the open procedure in children. The present study aims to address this question by comparing the postoperative outcomes of children who underwent minimally invasive versus open esophageal replacement procedures at single-center and multicenter levels.

Interventions

OTHERobservation of postoperative leak, stenosis, mortality

detect complications in both groups

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

All children undergoing oesophageal replacement aged one to 18 years. Due to 1. long gap esophageal atresia 2. caustic ingestion 3. congenital esophageal stenosis or strictures

Exclusion criteria

* patient who underwent previous esophageal replacement operations.

Design outcomes

Primary

MeasureTime frameDescription
Anastamotic leaks2 yearsIncidence of anastamotic leak which is identified clinically in both groups

Secondary

MeasureTime frameDescription
Anastamotic stricture2 yearsIncidence of symptomstic strictures which is identified by upper barium studies
Mortality2 yearsNumber of patient who die intraoperative and post operative in both groups

Countries

Egypt

Contacts

Primary ContactAhmed Maher, Msc.
ahmedmaherali31@gmail.com01026338229
Backup ContactMahmoud Mohamed Mostafa, MD
mmostafa@aun.edu.eg01005010897

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026