Cognitive Decline
Conditions
Keywords
aging, cognition, cognitive-motor training, Nordic walking
Brief summary
Understanding how to delay age-related physical and mental declines is an issue for aging research. It has been shown that isolated aerobic, coordination and cognitive training improve brain functions and cognitive performances. Moreover, the combination of them leads to greater effects. Different combination modalities are possible: training programs demanding cognitive resources within the activity performed in a natural environment like Nordic Walking (or Tai chi, Dance...); or as in a conceptually-grounded circuit training where training components are systematically combined and their intensity controlled. The aim of this study is to compare three training programs: a Nordic walking one (NW), and two conceptual grounded, circuits training (CT-c; CT-fit). CT-c implemented by dual-task (DT) exercises, while CT-fit characterized by cognitive charge embodied in the movements through the use of technology. An improvement in physical, motor, and cognitive functions is expected by all three groups. However, our primary hypothesis is that the CT-fit will impact executive functions more. 45 healthy independent living community dwellers participants aged 65 to 80 will be recruited. Participants will be included after a general medical examination (geriatric screening and cycle-ergometer maximal effort test). The main exclusion criteria are signs of cognitive impairment, (MMSE \<26/30), and physical impairments. Participants will be randomly divided into the 3 groups (NW, CT-c, CT-fit): The training program will last 8 weeks, 1 hour 3 times a week. Pre and post-tests will include cognitive assessment (MoCA; TMT; Stroop task, Happy Neuron™ working memory test, Rey Complex Figure copy task and dual-task capacities through the DT-OTMT); motor fitness assessment (Bipedal upright standing, Unipedal balance test, walking speed and size of the base of support, Timed Up & Go, Chair sit and reach test and Four square stepping test) and physical assessment (10 m incremental shuttle walking test, maximal handgrip force, 30s chair rise stand). Improving cognitive functions by adding new technology embodied in a systematically combined training (exergame), would result to be the best solution to optimize training for aging people.
Interventions
OTHERTechnology-assisted circuit training
Circuit training assisted by Fitlight™ 3 times a week for one hour during 8 weeks
OTHERConventional circuit training
Conventional circuit training including single and dual task 3 times a week for one hour during 8 weeks
OTHERNordic walking
Classic nordic walking 3 times a week for one hour during 8 weeks
Sponsors
Aix Marseille Université
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
65 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Considered apt for moderate physical activity practice (validated by a maximal VO2 cycle-ergometer test by a cardiologist) * Sedentary or moderately active (objectified by the categories obtained at the IPAQ) * Cognitively healthy (objectified by a score at the MMSE of 26 and above)
Exclusion criteria
* Colorblindness * Uncorrected earing and/or visual impairment * Presence of a known psychiatric or neurologic condition * Under psychotropic treatment or beta-blockers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in working memory function through HappyNeuron Software | Through study completion, an average of 9 months | Assessment for changing in working memory function tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in inhibition processes through Stroop task test | Through study completion, an average of 9 months | Assessment for changing of inhibition processes tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in switching capacities through Trial Making Test part A and part B (TMT-A and TMT-B) | Through study completion, an average of 9 months | Assessment for changing of switching capacities tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in visuospatial capacities through Rey complex Figure copy task | Through study completion, an average of 9 months | Assessment for changing of visuospatial capacities tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in dual task capacities through Walking Oral Trail Making Test part A and part B (OTMT-A and OTMT-B) | Through study completion, an average of 9 months | Assessment for chainging for dual task capacities tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in global cognition capacity through the Moca test | Through study completion, an average of 9 months | Assessment for changing for general cognition tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in balance capacities through Bipedal upright standing and Unipedal leg stance tests | Through study completion, an average of 9 months | Assessment for balance using a force platform for the bipedal upright standing (AMTI, Advanced Mechanical Technology, Inc., MA, USA). Both assessments tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in cardiovascular capacities through Shuttle walk test | Through study completion, an average of 9 months | Assessment for cardiovascular capacities tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in Gait pattern assessment | Through study completion, an average of 9 months | Assessment to test gait pattern using a Gait rite (walking at usual speed on a gait rite - GAITRite system, CIR Systems, Havertown, PA, United States) tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in functional mobility through the Timed Up & Go test | Through study completion, an average of 9 months | Assessment for functional mobility tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes for flexibility through the Chair-sit and reach test | Through study completion, an average of 9 months | Assessment for functional flexibility tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in motor coordination through the Four- Square Stepping test | Through study completion, an average of 9 months | Assessment for functional motor coordination tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
| Changes in muscular strength through Maximal handgrip force test | Through study completion, an average of 9 months | Assessment for muscular strength (using JAMAR® hand dynamometer) tested within the 4 weeks before the intervention (8 weeks of duration) and within the 4 weeks after the intervention ended. Up to 5 months for the results analysis and manuscript writing. |
Countries
France
Outcome results
None listed