Pelvi Ureteric Junction Obstruction or Ureteral Stricture
Conditions
Brief summary
Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
Detailed description
A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter. after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis. Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.
Interventions
PROCEDUREbuccal mucosal graft to repair iatrogenic PUJO
Augmented buccal mucosal graft anastomosis to repair iatrogenic PUJO or long segment ureteric stricture disease
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
20 patients with iatrogenic pelviureteric junction obstruction or ureteric stricture disease
Eligibility
Sex/Gender
ALL
Age
No minimum to 60 Years
Healthy volunteers
No
Inclusion criteria
\- any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture
Exclusion criteria
* elderly patients unfit for general anaesthesia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants with patent renal pelvis and ureter after surgery. | 3 months | 3 months after surgery Diuretic renography will be done to judge patency of the pelvis and ureter and resolution of hydronephrosis |
Outcome results
None listed