Central Venous Catheters, Central Venous Catheter Thrombosis, Intensive Care Unit, Thrombosis, Venous
Conditions
Brief summary
This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters.
Detailed description
Central venous catheter (CVC) is now indispensable in the monitoring and care of patients in intensive care (ICU). Unfortunately, one of the complications of its positioning is catheter-related thrombosis (CRT) and its consequences. Despite the widespread use of CVC and the extensive literature describing its complications, areas of uncertainty regarding the onset, treatment and prevention of CRT persist, especially with regard to asymptomatic thrombosis. This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters. The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU.
Interventions
DIAGNOSTIC_TESTultrasound
ultrasound of the central veins of the neck and chest and a (compression ultra-sound) CUS of the femoral veins will be performed bilaterally
Sponsors
Policlinico Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients over the age of 18 * admitted to intensive care who have for clinical reasons need to place a central venous catheter * signing of informed consent
Exclusion criteria
* patients under 18 years of age * Known cancer status * Congenital thrombophilia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of patients developing Catheter related thrombosis and Incidence of CRT in patients in ICU | Until CVC removal | The main objective of this study is to assess the proportion of patients developing CRT (proportion) and the incidence of CRT (rate expressed in catheter events/days) in patients in ICU. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of various types of thrombotic apposition | Until CVC removal | The proportion of various types of thrombotic apposition |
| Deep venous thrombosis (DVT) proportion and Incidence | Until CVC removal | The proportion of patients developing DVT and the incidence of catheter-related DVT (rate) in patients in ICU carrying CVC. |
| the association of thrombosis with alterations of hemocoagulative parameters | Until CVC removal | the association of thrombosis with alterations of hemocoagulative parameters |
| describe the clinical measures that have been taken following the diagnosis of CRT.describe the clinical measures that have been taken following the diagnosis of CRT. | Until CVC removal | describe the clinical measures that have been taken following the diagnosis of CRT. |
Countries
Italy
Outcome results
None listed